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P3440

Sigma-Aldrich

Polyoxyethylene (40) stearate

Synonym(e):

Myrj 52

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About This Item

CAS-Nummer:
9004-99-3
MDL-Nummer:
MFCD00148007
UNSPSC-Code:
12161900
NACRES:
NA.25

Beschreibung

non-ionic

Form

powder

Anwendung(en)

detection

InChI

1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3

InChIKey

RFVNOJDQRGSOEL-UHFFFAOYSA-N

Allgemeine Beschreibung

Polyoxyethylene (40) stearate is a neutral surfactant.

Anwendung

Polyoxyethylene (40) stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers. It has also been used in a study to investigate its effects on multidrug resistance (MDR).

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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Effects of polyoxyethylene (40) stearate on the activity of P-glycoprotein and cytochrome P450.
Zhu, S., et al.
European Journal of Pharmaceutical Sciences, 37, 8-8 (2009)
Lingying Luo et al.
The AAPS journal, 9(3), E329-E335 (2008-01-04)
Multidrug resistance (MDR) is one of the major obstacles limiting the efficacy of cancer chemotherapy. Identification of new and effective MDR reversal agents is needed. In this study, the effects of polyoxyethylene 40 stearate (PS40) on MDR were evaluated via
Alexandra Kosareva et al.
Ultrasound in medicine & biology, 47(9), 2664-2675 (2021-06-20)
Clinical translation of ultrasound molecular imaging will depend on the development of binders that can easily be generated, manufactured and coupled, and that are compatible with in vivo use. We describe targeted microbubbles (MBs) using designed ankyrin repeat proteins (DARPins)
Michalakis Savva et al.
Colloids and surfaces. A, Physicochemical and engineering aspects, 325(1-2), 1-6 (2009-07-18)
The feasibility of a method based on mass preservation [G. Schwarz, J. Zhang, Chem. Phys. Lipids, 110 (2001) 35-45] to determine the solubility of Cholesterol in water from monomolecular films on air/water interface was investigated. Using a mass balance equation
Mona M A Abdel-Mottaleb et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 79(1), 36-42 (2011-05-12)
Lipid nanocapsules (LNC) are colloidal carriers providing controlled release profiles and improved bioavailability for many drug substances and diverse administration routes. However, they have not been explored before for transdermal application. Here, we study the behavior of LNC as a
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