M108

(−)-MK-801 hydrogen maleate

≥98% (HPLC)

• Synonym(e): (5R,10S)-(–)-5-Methyl-10,11-dihydro-5H-dibenzo­[a,d]­cyclo­hepten-5,10-imine hydrogen maleate
• Empirische Formel (Hill-System): C₁₆H₁₅N · C₄H₄O₄
• CAS-Nummer: 77086-19-2
• Molekulargewicht: 337.37
• MDL-Nummer: MFCD00082466
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24277961

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: solid
• Optische Aktivität: [α]25/D −117.7°, c = 1 in methanol(lit.)
• Farbe: white
• Löslichkeit: DMSO: >20 mg/mL
• Lagertemp.: room temp
• SMILES String: [H]\C(=C(/[H])C(O)=O)C(O)=O.[H][C@@]12Cc3ccccc3[C@@](C)(N1)c4ccccc24
• InChI: 1S/C16H15N.C4H4O4/c1-16-13-8-4-2-6-11(13)10-15(17-16)12-7-3-5-9-14(12)16;5-3(6)1-2-4(7)8/h2-9,15,17H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-,16+;/m0./s1
• InChIKey: QLTXKCWMEZIHBJ-FWHYOZOBSA-N
• Angaben zum Gen: human ... GRIN1(2902) , GRIN2C(2905) , GRIN2D(2906) , GRIN3A(116443) , GRIN3B(116444) , GRINA(2907) ; mouse ... GRIN1(14810) , GRIN2C(14813) , GRIN2D(14814) , GRIN3A(242443) , GRIN3B(170483) , GRINA(66168) ; rat ... GRIN1(24408) , GRIN2C(24411) , GRIN2D(24412) , GRIN3A(191573) , GRIN3B(170796) , GRINA(266668)

Beschreibung

Allgemeine Beschreibung

(-)-MK-801 hydrogen maleate is a less potent stereoisomer of (+)-MK-801.[1]

Biochem./physiol. Wirkung

Less active enantiomer of (+)-MK-801 hydrogen maleate

MK-801 functions as a selective non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist.[2][1]

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)