F9261

Flunitrazepam

• Synonym(e): 5-(2-Fluorphenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2(1H)-on, Ro 5-4200
• Empirische Formel (Hill-System): C₁₆H₁₂FN₃O₃
• CAS-Nummer: 1622-62-4
• Molekulargewicht: 313.28
• EG-Nummer: 216-597-8
• MDL-Nummer: MFCD00057906
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24894993
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 200
• Arzneimittelkontrolle: USDEA Schedule IV; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
• Löslichkeit: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1 mg/mL; DMF: soluble; ethanol: soluble
• Ersteller: Roche
• SMILES String: CN1C(=O)CN=C(c2ccccc2F)c3cc(ccc13)[N+]([O-])=O
• InChI: 1S/C16H12FN3O3/c1-19-14-7-6-10(20(22)23)8-12(14)16(18-9-15(19)21)11-4-2-3-5-13(11)17/h2-8H,9H2,1H3
• InChIKey: PPTYJKAXVCCBDU-UHFFFAOYSA-N
• Angaben zum Gen: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879) ; rat ... Gabra2(29706)

Beschreibung

Biochem./physiol. Wirkung

Hypnotic; anxiolytic; ligand for the GABA_A receptor benzodiazepine modulatory site.

Leistungsmerkmale und Vorteile

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H336,H412
• P-Sätze: P261 - P264 - P271 - P273 - P301 + P312 - P304 + P340 + P312
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Chronic 3 - STOT SE 3
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves