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Merck

E6902

Sigma-Aldrich

Elastin, soluble from human aorta

lyophilized powder

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About This Item

CAS-Nummer:
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352202

Biologische Quelle

human aorta

Qualitätsniveau

Form

lyophilized powder

Methode(n)

cell culture | mammalian: suitable

Verunreinigungen

salt, free

UniProt-Hinterlegungsnummer

Lagertemp.

2-8°C

InChI

1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1

InChIKey

DPUYCSDGMSDKKV-MKBYFEBXSA-N

Angaben zum Gen

human ... ELN(2006)

Biochem./physiol. Wirkung

Elastin, along with fibrillin, is responsible for the elastic properties of skin and arteries. Reported inhibitor of Clostridial collagenase.
Reported inhibitor of Clostridial collagenase

Angaben zur Herstellung

Prepared from E6777 using the method of Partrige, et al.[1]

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Jinzhi Li et al.
BMC cancer, 20(1), 217-217 (2020-03-17)
Colorectal cancer (CRC) is the most common cancer and a leading cause of death worldwide. Extracellular matrix (ECM) proteins regulate tumor growth and development in CRC. Elastin (ELN) is a component of ECM proteins involved in the tumor microenvironment. However
E H Sage et al.
Advances in experimental medicine and biology, 79, 291-312 (1977-01-01)
The aortae of a number of vertebrates and invertebrates were tested for the presence of elastin to determine when this protein first appears phylogenetically. Using several criteria, including amino acid composition, presence of desmosines, and histological characteristics, we found that
Hui Li et al.
Journal of anatomy, 236(1), 171-179 (2019-08-31)
Distinguishing arteries from veins in vivo has a great significance in clinical practices and preclinical studies. Optical imaging methods such as two-photon microscopy can provide high-resolution morphological information of tissue and are therefore extremely suitable for imaging small blood vessels.
The chemistry of connective tissues. 2. Soluble proteins derived from partial hydrolysis of elastin.
S M PARTRIDGE et al.
The Biochemical journal, 61(1), 11-21 (1955-09-01)
Aleksandra Kuzan et al.
Folia histochemica et cytobiologica, 59(1), 8-21 (2021-02-10)
Extracellular matrix (ECM) proteins have been associated with atherosclerotic complications, such as plaque rupture, calcification and aneurysm. It is not clear what role different types of collagen play in the pathomechanism of atherosclerosis. The aim of the study was to

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