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D1878

Sigma-Aldrich

2,6-Dichlor-phenolindophenol Natriumsalz Hydrat

Powder, BioReagent

Synonym(e):

2,6-Dichlor-N-(4-hydroxyphenyl)-1,4-benzochinonimin Natriumsalz, 2,6-Dichlorindophenol Natriumsalz, DCIP, DPIP

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5 G
CHF 126.00
25 G
CHF 508.00

CHF 126.00

Voraussichtliches Versanddatum25. März 2025

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5 G
CHF 126.00
25 G
CHF 508.00

About This Item

Empirische Formel (Hill-System):
C12H6Cl2NNaO2 · xH2O
CAS-Nummer:
1266615-56-8
Molekulargewicht:
290.08 (anhydrous basis)
Beilstein:
3641229
EG-Nummer:
210-640-4
MDL-Nummer:
MFCD00150014
UNSPSC-Code:
12171500
PubChem Substanz-ID:
57654075
NACRES:
NA.47

CHF 126.00

Voraussichtliches Versanddatum25. März 2025

Bulk-Bestellung anfordern

Produktbezeichnung

2,6-Dichlor-phenolindophenol Natriumsalz Hydrat, suitable for vitamin C determination, BioReagent

Produktlinie

BioReagent

Qualitätsniveau

200

Form

powder

Löslichkeit

H2O: soluble 10 mg/mL, clear, blue to very deep blue

Eignung

suitable for vitamin C determination

Anwendung(en)

diagnostic assay manufacturing
food and beverages
hematology
histology

Lagertemp.

room temp

SMILES String

O.[Na+].[O-]c1ccc(cc1)\N=C2/C=C(Cl)C(=O)C(Cl)=C2

InChI

1S/C12H7Cl2NO2.Na.H2O/c13-10-5-8(6-11(14)12(10)17)15-7-1-3-9(16)4-2-7;;/h1-6,16H;;1H2/q;+1;/p-1

InChIKey

XHSOLXWCGCVQHE-UHFFFAOYSA-M

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Verwandte Kategorien

Allgemeine Beschreibung

2,6-Dichlorindophenolnatriumsalzhydrat ist ein blauer Redox-Farbstoff.

Anwendung

2,6-Dichlorindophenolnatriumsalzhydrat eignet sich für die Bestimmung von Vitamin C. 2,6-Dichlorindophenol (DCIP) kann in folgenden Studien verwendet werden:
  • Als Redox-Farbstoff zur Untersuchung der Effizienz von Gold-Nanopartikeln (Au-NP) für die Enzymaktivität der Glucose-Oxidase (GOx).[1]
  • Zur Herstellung von UVB-spezifischen Dosimetern.[2]
  • Quantifizierung von Vitamin C (L-Ascorbinsäure) in Fruchtsäften.[3]
  • Als Substrate im NQO1-Assay zur spektrophotometrischen Untersuchung der cytosolischen NQO1-Leberaktivität.[4]
  • Mitochondrialer Succinat-CoQ-Oxidoreduktase(-Komplex-II)-Aktivitäts-Assay.[5]

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCCK3015
BCCH8797
BCCD6459
BCCD6463
BCCD6464

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Spectrophotometric evaluation of gold nanoparticles as red-ox mediator for glucose oxidase.
Ramanaviciene A, et al.
Sensors and Actuators B, Chemical, 137(2), 483-489 (2009)
Andrew Mills et al.
The Analyst, 134(5), 845-850 (2009-04-22)
A UVB specific dosimeter is described comprising: a redox dye (2,6-dichloroindophenol, DCIP), a semiconductor (tin(IV) oxide, SnO(2)) and a sacrificial electron donor (glycerol) dispersed in a polymer (hydroxy ethyl cellulose, HEC) film. The dosimeter is blue in the absence of
Hanit Brenner-Lavie et al.
Biochimica et biophysica acta, 1777(2), 173-185 (2007-11-13)
Deleterious effects of dopamine (DA) involving mitochondrial dysfunction have an important role in DA-associated neuronal disorders, including schizophrenia and Parkinson's disease. DA detrimental effects have been attributed to its ability to be auto-oxidized to toxic reactive oxygen species. Since, unlike
Misty Prince et al.
Toxicology letters, 185(3), 180-186 (2009-01-20)
Naturally occurring coumarins possess anti-carcinogenic activities in part by inducing carcinogen-detoxifying enzymes glutathione S-transferase (GST) and/or NAD(P)H quinone oxidoreductase (NQO1). Our goal was to determine whether citrus coumarins induce hepatic GST and/or NQO1 via activation of Nrf2 and the antioxidant
Georgina Fabro et al.
Plant physiology and biochemistry : PPB, 154, 268-276 (2020-06-24)
Proline dehydrogenase (ProDH) is a flavoenzyme that catalyzes the oxidation of proline (Pro) into Δ1-pyrroline-5-carboxylate (P5C). In eukaryotes, ProDH coordinates with different Pro metabolism enzymes to control energy supply or stress responses signaling. Heterologous expression and crystallization of prokaryotic enzymes
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Questions

1–8 of 8 Questions  

  1. Has Sigma Aldrich performed solution stability studies for Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 answer

    1. No. Unfortunately, we have not performed solution stability studies on this product.

      Helpful?

  2. Has Product D1878, 2,6-Dichloroindophenol sodium salt hydrate, been used as a pH or redox indicator?

    1 answer

    1. Yes. Conn's Biological Stains indicates Dichloroindophenol sodium salt in acid is  red and blue in alkali. The product is colorless when reduced.

      Helpful?

  3. Other than use as a reagent for determination of Vitamin C, are there other reported uses of Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 answer

    1. Yes. Conn's Biological Stains indicates Dichloroindophenol sodium salt has been used as an electron receptor, for use in demonstrating NADPH diaphorase and to stain glutathione reductase electrophoresis gels.

      Helpful?

  4. Are there published references for Dichloroindophenol sodium salt being used for the determination of Vitamin C?

    1 answer

    1. Yes. Please see: W. Horowitz ed. Official Methods of Analysis of the AOAC Washington D.C. , 777, (1970) and  K. Hiromi et al., Anal. Biochem. 101, 421, (1980).

      Helpful?

  5. Are there substances known to interfere in Vitamin C determination?

    1 answer

    1. Yes. Interfering substances are ferrous, stannous, and cuprous sulfite or thiosulfate ions, and SO2.

      Helpful?

  6. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  7. What is the solubility for Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 answer

    1. During quality control testing, Sigma Aldrich tests solubility at 10 mg/mL in water.  Conn's Biological Stains, 10th Edition states that dichloroindophenol sodium salt is soluble up to 3% in water and up to 2% in ethanol.

      Helpful?

  8. Are the absorbance maxima and the extinction coefficients available for Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 answer

    1. Our Analytical Department has run absorbance spectra on many lots of D1878. Using 0.1 M phosphate buffer, pH 8.3 as the solvent, absorbance maxima in the range of 600-605 nm and a mM extinction coefficient of 18.0-19.7 have been reported.

      Helpful?

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