C2832

Cholesteryl 3β-N-(di­methyl­amino­ethyl)­carbamate hydrochloride

≥95%

• Synonym(e): 3β-[N-(Dimethylaminoethane)­carbamoyl]­cholesterol, DC-Chol
• Empirische Formel (Hill-System): C₃₂H₅₇ClN₂O₂
• CAS-Nummer: 166023-21-8
• Molekulargewicht: 537.26
• MDL-Nummer: MFCD00467173
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24892536
• NACRES: NA.77

Eigenschaften

• Assay: ≥95%
• Form: powder
• Lagertemp.: −20°C
• SMILES String: Cl[H].[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC(=O)NCCN(C)C)[C@H](C)CCCC(C)C
• InChI: 1S/C32H56N2O2.ClH/c1-22(2)9-8-10-23(3)27-13-14-28-26-12-11-24-21-25(36-30(35)33-19-20-34(6)7)15-17-31(24,4)29(26)16-18-32(27,28)5;/h11,22-23,25-29H,8-10,12-21H2,1-7H3,(H,33,35);1H/t23-,25+,26+,27-,28+,29+,31+,32-;/m1./s1
• InChIKey: ISXSJGHXHUZXNF-LXZPIJOJSA-N

Beschreibung

Anwendung

Cholesteryl 3β-N-(di­methyl­amino­ethyl)­carbamate hydrochloride has been used as a bilayer-membrane stabiliser[1] and for nucleic acid transfer.[2]

This cationic cholesterol derivative forms liposomes with L-α-phosphatidylethanolamine, dioleoyl, that efficiently transfect mammalian cell lines.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)