5-Bromo-2´-deoxyuridine is stable in solution for 6 months when stored -20°C.
Alle Fotos(4)
Wichtige Dokumente
B9285
5-Brom-2′-deoxyuridin
BioUltra, ≥99%
Synonym(e):
2′-Deoxy-5-bromuridin, 5-BrdU, 5-Brom-1-(2-deoxy-β-D-ribofuranosyl)-uracil, 5-Bromuracil-deoxyribosid, BUdR
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Größe auswählen
50 MG
CHF 43.00
250 MG
CHF 109.00
1 G
CHF 401.00
CHF 43.00
Voraussichtliches Versanddatum17. März 2025
Alle Fotos(4)
Größe auswählen
Ansicht ändern
50 MG
CHF 43.00
250 MG
CHF 109.00
1 G
CHF 401.00
About This Item
Empirische Formel (Hill-System):
C9H11BrN2O5
CAS-Nummer:
Molekulargewicht:
307.10
Beilstein:
30395
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41106305
PubChem Substanz-ID:
NACRES:
NA.51
CHF 43.00
Voraussichtliches Versanddatum17. März 2025
Empfohlene Produkte
Biologische Quelle
synthetic (organic)
Qualitätsniveau
Produktlinie
BioUltra
Assay
≥99%
Form
powder
Verunreinigungen
≤0.005% Phosphorus (P)
≤0.1% Insoluble matter
Glührückstand
≤0.1%
mp (Schmelzpunkt)
191-194 °C (dec.) (lit.)
Löslichkeit
NH4OH: 0.1 M at 20 °C, clear, colorless
Kationenspuren
Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%
Lagertemp.
−20°C
SMILES String
OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(Br)C(=O)NC2=O
InChI
1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChIKey
WOVKYSAHUYNSMH-RRKCRQDMSA-N
Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich
Allgemeine Beschreibung
5′-Bromo-2-deoxyuridine (BrdU) is a carcinogen that may be absorbed by skin or inhalation. BrdU solutions are sensitive to light.[1]
Anwendung
5-Bromo-2′-deoxyuridine has been used:
- to label proliferating cells in pregnant mice in cell proliferation assay[2]
- to study the time course of cell proliferation at various times following ischemia[3], to confirm re-entry of MKI67+ cells in cell cycle to germ cells[4]
- in 5′-Bromo-2′Deoxyuridine (BrdUrd) staining of fibroblasts[5]
Biochem./physiol. Wirkung
5′-Bromo-2-deoxyuridine (BrdU) staining is predominantly used to observe the multiplication of tumor cells and other tissues in vivo.[6]
5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
Thymidin-Analogon zur Verwendung als Mutagen in der Genforschung. Selektiver Einbau in zelluläre DNA während der S-Phase.
Signalwort
Danger
H-Sätze
Gefahreneinstufungen
Muta. 1B - Repr. 2
Lagerklassenschlüssel
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Kunden haben sich ebenfalls angesehen
Histological, cellular and behavioral assessments of stroke outcomes after photothrombosis-induced ischemia in adult mice
Li H, et al.
BMC Neuroscience, 15(1), 1-13 (2014)
Retinoic Acid Induces Multiple Hallmarks of the Prospermatogonia-to-Spermatogonia Transition in the Neonatal Mouse
Busada JT, et al.
Biology of Reproduction, 90(3) (2014)
Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors
Kress TR, et al.
Cancer research, 76(12), 3463-3472 (2016)
Cell Proliferation and Apoptosis (2003)
Non-canonical Cyclic Nucleotides (2017)
-
For how long is Product B9285, 5-Bromo-2´-deoxyuridine, stable in solution?
1 answer-
Helpful?
-
-
What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Helpful?
-
-
In what solvents is Product B9285, 5-Bromo-2´-deoxyuridine, soluble?
1 answer-
Solubility information for 5-bromo-2´-deoxyuridine can be found on the product information sheet (under Documents, above).
Helpful?
-
-
What is the shelf life of Product No. B9285 (5-bromo-2´-deoxyuridine)?
1 answer-
Sigma-Aldrich does not assign an expiration date to this product; it is guaranteed for one year from the date of shipment.
Helpful?
-
-
Can Product B9285, 5-Bromo-2´-deoxyuridine, be injected into animals?
1 answer-
Sigma has not injected animals with solutions of this compound, so we do not have a stepwise procedure for you. However, this application has been reported in the literature. Please see the cited references below, which you may find useful. Several references cite the use of Product No. B9285 in their protocols.1. Yin, X-X, et al., Expression of active caspase-3 in mitotic and postmitotic cells of the rat forebrain. J. Comp. Neurol., 433(1), 4-22 (2001). Injected into mice at 50 mg/kg.2. Dackor, R.T., et al., Hydrops Fetalis, Cardiovascular Defects, and Embryonic Lethality in Mice Lacking the Calcitonin Receptor-Like Receptor Gene. Mol. Cell. Biol., 26(7), 2511-2518 (2006). Injected into mice at 100 mg/kg.3. Farris, S.M., et al., Larval and Pupal Development of the Mushroom Bodies in the Honey Bee, Apis mellifera. J. Comp. Neurol., 414, 97-113 (1999). A 25 mg/mL solution was injected into bee larvae, prepupae, and pupae.4. Gaiano, N., et al., Radial Glial Identity Is Promoted by Notch1 Signaling in the Murine Forebrain. Neuron, 26(2), 395-404 (2000). A 20 mg/mL solution was injected into mice.
Helpful?
-
Active Filters
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
Setzen Sie sich mit dem technischen Dienst in Verbindung.
