B3251 is a laboratory research grade product. It has two purity specifications, Titration by perchloric acid with a purity specification of 97 - 102 % and a TLC purity with a specification of ≥ 98 %. The CAS number for B3251 - Berberine chloride form is synonymous with Benzodioxide, Berberine HCl, Natural Yellow 18.
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Wichtige Dokumente
B3251
Berberin Chlorid-Form
Synonym(e):
Natural Yellow 18
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About This Item
Empirische Formel (Hill-System):
C20H18ClNO4
CAS-Nummer:
Molekulargewicht:
371.81
Farbindexnummer:
75160
Beilstein:
3836585
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12171500
PubChem Substanz-ID:
NACRES:
NA.32
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Empfohlene Produkte
Form
powder
Qualitätsniveau
Löslichkeit
methanol: soluble
SMILES String
COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]
InChI
1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
InChIKey
VKJGBAJNNALVAV-UHFFFAOYSA-M
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Allgemeine Beschreibung
Berberine Chloride form or Natural Yellow 18, is also known as 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo (5,6-a) quinolizinium is a benzyl tetra isoquinoline plant alkaloid. Berberine contains a quaternary base and is commercially available in berberine chloride form.
Anwendung
Berberine Chloride is a fluorescent stain used to stain heparin in mast cells. Berberine upregulates the expression of Pgp in hepatoma cells.
Fluoreszenzfarbstoff für Heparin in Mastzellen
Biochem./physiol. Wirkung
Ein Alkaloid mit schwachen antibiotischen Eigenschaften. Substrat für MDR-Effluxpumpen. Antimikrobielle Aktivitäten von Berberin werden durch den MDR-Inhibitor 5´-Methoxyhydnocarpin (5´-MHC) potenziert. Berberin hochreguliert die Expression von Pgp in Hepatomzellen. Die Behandlung mit Berberin führt potenziell zu einer reduzierten Anreicherung von Chemotherapeutika.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Kunden haben sich ebenfalls angesehen
Wan-Jin Zhang et al.
Bioorganic & medicinal chemistry, 15(16), 5493-5501 (2007-06-19)
The interaction of berberine and its 9-substituted derivatives with human telomeric DNA d[G(3)(T(2)AG(3))(3)](telo21) has been investigated via CD spectroscopy, fluorescence spectroscopy, PCR-stop assay, competitive dialysis, and telomerase repeat amplification protocol (TRAP) assay. The results indicated that these semisynthesized compounds could
Xiaoling Zhang et al.
Cancer research, 70(23), 9895-9904 (2010-10-12)
Berberine, a natural product derived from a plant used in Chinese herbal medicine, is reported to exhibit anticancer effects; however, its mechanism of action is not clearly defined. Herein, we demonstrate that berberine induces apoptosis in acute lymphoblastic leukemia (ALL)
Ying-Hong Li et al.
Journal of medicinal chemistry, 52(2), 492-501 (2008-12-19)
Twenty-nine derivatives of berberine (1) or pseudoberberine (2) were designed, semisynthesized, and evaluated for their up-regulatory activity on the low-density-lipoprotein receptor (LDLR) expression. SAR analysis revealed that (i) the methylenedioxy group at the 2- and 3-position is an essential element
Gil Belofsky et al.
Journal of natural products, 69(2), 261-264 (2006-02-28)
Two new 2-arylbenzofuran aldehydes (1 and 2) and three known phenolic compounds (3-5) were isolated from organic extracts of Dalea spinosa. These compounds were evaluated for their intrinsic antimicrobial activity and their ability to perform as multidrug-resistance inhibitors by potentiating
Inhibitors of prolyl oligopeptidases for the therapy of human diseases: defining diseases and inhibitors.
Janice Lawandi et al.
Journal of medicinal chemistry, 53(9), 3423-3438 (2010-01-12)
Artikel
Protein-based drug transporters are expressed in Sf9 cells. Understanding the specific mechanisms of tumor cell transporters is an essential aspect of chemotherapeutic drug design.
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I want to ask you about this compound whether it is API. And what is the purity percentage. Further. I want to inquire about this compound. Is it same berberine hydrochloride
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