1065210

Berberinchlorid

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Berberin Chlorid-Form, Natural Yellow 18
• Empirische Formel (Hill-System): C₂₀H₁₈ClNO₄
• CAS-Nummer: 633-65-8
• Molekulargewicht: 371.81
• Farbindexnummer: 75160
• Beilstein: 3836585
• MDL-Nummer: MFCD00011939
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329748923
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: berberine
• Hersteller/Markenname: USP
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• SMILES String: COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]
• InChI: 1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
• InChIKey: VKJGBAJNNALVAV-UHFFFAOYSA-M

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Berberine chloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Coptis Species Rhizome
• Coptis Species Rhizome Dry Extract
• Coptis Species Rhizome Powder
• Goldenseal
• Indian Barberry Stem
• Indian Barberry Stem Dry Extract
• Indian Barberry Stem Powder

Fluoreszenzfarbstoff für Heparin in Mastzellen

Biochem./physiol. Wirkung

Ein Alkaloid mit schwachen antibiotischen Eigenschaften. Substrat für MDR-Effluxpumpen. Antimikrobielle Aktivitäten von Berberin werden durch den MDR-Inhibitor 5´-Methoxyhydnocarpin (5´-MHC) potenziert. Berberin hochreguliert die Expression von Pgp in Hepatomzellen. Die Behandlung mit Berberin führt potenziell zu einer reduzierten Anreicherung von Chemotherapeutika.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable