Synthetic peptide directed towards the N terminal region of human ZFP91
Biochem./physiol. Wirkung
ZFP91 (ZNF757) is a member of zinc finger proteins that contain C2H2-type domains. It regulates the non-canonical NF-κB signaling induced by lymphotoxin-β receptor. An abundant expression of ZFP91 mRNA has been observed in prostate diseases including prostate cancer. ZFP91 may have a role in cell proliferation and survival and is a potential molecular marker for acute myelogenous leukemia.
Sequenz
Synthetic peptide located within the following region: PQAAKSPSPVQGKKSPRLLCIEKVTTDKDPKEEKEEEDDSALPQEVSIAA
Physikalische Form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Pathology oncology research : POR, 20(2), 453-459 (2013-11-26)
In search for novel molecular targets in benign prostate hyperplasia (BPH), a PCR Array based screening of 84 genes was performed. Of those, expression of ZFP91 (ZFP91 zinc finger protein) was notably upregulated. Limited data concerning the function of ZFP91
International journal of oncology, 22(6), 1217-1223 (2003-05-10)
To elucidate mechanisms leading to acute myelogenous leukemia (AML), to find sensitive markers and novel targets for drug therapy, and to allow choice of suitable chemotherapy for each affected individual, we previously compared expression of mRNA from mononuclear cells of
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