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Dokumente

17797

Sigma-Aldrich

Physcion

≥98.0% (TLC)

Synonym(e):

1,8-Dihydroxy-3-methoxy-6-methyl-anthrachinon, 6-O-Methylemodin, 6-Methoxychrysophansäure, Emodin-3-methylether, Parietin, Rheochrysidin

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About This Item

Empirische Formel (Hill-System):
C16H12O5
CAS-Nummer:
521-61-9
Molekulargewicht:
284.26
Beilstein:
6770499
EG-Nummer:
208-315-7
MDL-Nummer:
MFCD00017374
UNSPSC-Code:
85151701
PubChem Substanz-ID:
57647675
NACRES:
NA.25

Assay

≥98.0% (TLC)

Wirkungsspektrum von Antibiotika

fungi

SMILES String

COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1

InChI

1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3

InChIKey

FFWOKTFYGVYKIR-UHFFFAOYSA-N

Angaben zum Gen

human ... ELA2(1991)

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Anwendung

Physcion can be used to study antibiotics, antifungals, bioactive small molecules and cell biology. Physcion has been used in a study to test the cytotoxicity of juglanthraquinone C on human cancer cells. Physcion has also been used in a study that investigated the metabolic regulatory effects of Rheum undulatum in a high-fat diet model.

Biochem./physiol. Wirkung

Anthraquinone-derivative found in medicinal herbs.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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Yao Yao et al.
Apoptosis : an international journal on programmed cell death, 17(8), 832-841 (2012-04-10)
Juglanthraquinone C (1,5-dihydroxy-9,10-anthraquinone-3-carboxylic acid, JC), a naturally occurring anthraquinone isolated from the stem bark of Juglans mandshurica, shows strong cytotoxicity in various human cancer cells in vitro. Here, we first performed a structure-activity relationship study of six anthraquinone compounds (JC
Phil-Dong Moon et al.
Molecules (Basel, Switzerland), 24(8) (2019-04-18)
Physcion is well known for the treatment of carcinoma. However, the therapeutic effect of physcion on atopic dermatitis (AD) through the inhibition of thymic stromal lymphopoietin (TSLP) level remains largely unknown. In this study, we investigated the anti-AD effect of
Simeon F Kouam et al.
Journal of natural products, 69(2), 229-233 (2006-02-28)
One new prenylated 1,4-anthraquinone and three new prenylated anthranols, named kengaquinone (1) and kenganthranols A (2), B (3), and C (4), were isolated from a hexane extract of the stem bark of Harungana madagascariensis. Six known compounds including anthraquinones, anthrones
Ming-Yi Shen et al.
PloS one, 6(11), e27480-e27480 (2011-11-17)
Plants provide a rich source of lead compounds for a variety of diseases. A novel approach combining phytochemistry and chemotaxis assays was developed and used to identify and study the mechanisms of action of the active compounds in F. japonica
Santosh Pandit et al.
Biofouling, 28(3), 279-287 (2012-03-23)
Polygonum cuspidatum is a plant with spreading rhizomes and numerous reddish-brown stems that has been used in Korean folk medicine to improve oral hygiene. Nevertheless, there are no reports related to its possible effect on the virulence of dental biofilms.
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