Direkt zum Inhalt
Merck

D5879

Sigma-Aldrich

Dimethylsulfoxid

ReagentPlus®, ≥99.5%

Synonym(e):

DMSO, Methylsulfoxid

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Lineare Formel:
(CH3)2SO
CAS-Nummer:
Molekulargewicht:
78.13
Beilstein:
506008
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12191502
PubChem Substanz-ID:
NACRES:
NA.21
Assay:
≥99.5%
Methode(n):
immunoblotting: suitable
bp:
189 °C (lit.)
Dampfdruck:
0.42 mmHg ( 20 °C)
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Dampfdichte

2.7 (vs air)

Qualitätsniveau

Dampfdruck

0.42 mmHg ( 20 °C)

Produktlinie

ReagentPlus®

Assay

≥99.5%

Form

liquid

Selbstzündungstemp.

573 °F

Expl.-Gr.

42 %, 63 °F

Methode(n)

immunoblotting: suitable

Verunreinigungen

≤0.1% water (Karl Fischer)

Brechungsindex

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp (Schmelzpunkt)

16-19 °C (lit.)

Löslichkeit

H2O: soluble(lit.)
acetone: soluble(lit.)
benzene: soluble(lit.)
chloroform: soluble(lit.)
ethanol: soluble(lit.)

Dichte

1.10 g/mL (lit.)

SMILES String

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChIKey

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Allgemeine Beschreibung

Dimethylsulfoxid ist ein amphipathisches Molekül, das sowohl in wässrigen als auch in organischen Lösungsmitteln löslich ist.[1] Es wird häufig als aprotisches Lösungsmittel[2] sowie als Reagens bei der organischen Synthese verwendet.[3]

Anwendung

DMSO wird als Medium zur Herstellung eines Chemolumineszenz-Reagens verwendet, das als Ersatz für im Handel erhältliche erweiterte Chemolumineszenz-Kits zur Verwendung bei Immunblotting-Verfahren verwendet werden kann.[4]

Biochem./physiol. Wirkung

Dimethylsulfoxid (DMSO) ist eine hochpolare Substanz, die als industrielles Lösungsmittel für organische und anorganische Chemikalien verwendet werden kann. Es wird zudem als Schutzmittel bei der Kaltlagerung von lebenden Zellen verwendet.[5][6] Außerdem ist es bei der Oxidation von Thiolen und Disulfiden zu Sulfonsäuren nützlich.[7]

Verpackung

Hinweis: D5879-1L in Glasflasche / D5879-1L-D in Polyflasche.

Vorsicht

Unterkühlt leicht und schmilzt langsam bei Raumtemperatur. Das verfestigte Produkt kann durch Erwärmen auf Raumtemperatur wieder verflüssigt werden, ohne dabei geschädigt zu werden.

Sonstige Hinweise

Informationen zur Mischbarkeit von Dimethylsulfoxid finden Sie unter folgendem Link:
Tabelle zur Mischbarkeit/Unmischbarkeit von Dimethylsulfoxid

Rechtliche Hinweise

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

188.6 °F - closed cup

Flammpunkt (°C)

87 °C - closed cup


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Die passende Version wird nicht angezeigt?

Wenn Sie eine bestimmte Version benötigen, können Sie anhand der Lot- oder Chargennummer nach einem spezifischen Zertifikat suchen.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Kunden haben sich ebenfalls angesehen

Lowe, O.G
The Journal of Organic Chemistry, 41 (1976)
Julia L Zehr et al.
Biology of reproduction, 72(5), 1087-1094 (2004-12-31)
This study investigated whether prenatal androgen exposure, social rank, and body weight are factors regulating pubertal development in outdoor-housed female rhesus monkeys. Subjects' mothers received injections of testosterone enanthate (20 mg/ wk), flutamide (an androgen receptor blocker, 30 mg/kg twice
Sun-A Ock et al.
Cell transplantation, 20(8), 1231-1239 (2011-02-08)
Dimethyl sulfoxide (DMSO), a commonly used cryoprotectant in cryopreservation procedures, is detrimental to viability of cells. In this view point, a comparative study was carried out to evaluate the effect of DMSO on porcine mesenchymal stem cells (pMSCs). We compared
M Bouquet et al.
Molecular reproduction and development, 40(1), 110-115 (1995-01-01)
In a previous study, we have shown that the cryopreservation of mouse oocytes caused increases in the rates of degeneration and of digynic polyploid embryos, while the fertility of frozen-thawed oocytes was decreased. In this study, we have attempted to
Activated dimethyl sulfoxide: useful reagents for synthesis.
Mancuso AJ and Swern D.
Synthesis, 1981(03), 165-185 (1981)

Questions

1–7 of 7 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. Is the DMSO (Dimethyl Sulfoxide) still considered usable if it was received in a frozen or solid form?

    1 answer
    1. Yes, DMSO (Dimethyl Sulfoxide) is still considered usable even if it was received in a frozen or solid form. The solidified DMSO can be easily re-liquefied by warming it to room temperature.

      Helpful?

  4. My application requires a dry solvent. How can I remove water that is present in Dimethyl sulfoxide, Product D5879?

    1 answer
    1. This product has a water content specification of not more than 0.1%, which may be low enough for your application. Other DMSO products may have more water present. Molecular sieves are typically zeolite compounds that strongly adsorb water and have carefully controlled pore sizes. If you would like, dried sieves may be placed into the bulk solvent container (about 5%-10% by volume) to remove most water.  Sigma-Aldrich offers 4 Å molecular sieves (e.g. product 334308), which would be effective in removing residual water from DMSO.

      Helpful?

  5. What is the molarity of Product D5879, Dimethyl sulfoxide?

    1 answer
    1. Pure solvents do not technically have a molarity (defined as moles of solute per liter of solution), since there is no solute distinct from the pure material. However, an effective molar concentration of 14.1M can be determined for this product, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

      Helpful?

  6. The Dimethyl sulfoxide, Product D5879,  I ordered arrived as a solid. Is the product still acceptable?

    1 answer
    1. Sigma-Aldrich ships many products, including DMSO, at ambient temperature. As a result product D5879 might arrive as a solid depending on the weather conditions during shipment. The melting point of DMSO is 16-19°C. Therefore, if the solid is allowed to warm to room temperature, it will melt without any impact on the quality of the product.

      Helpful?

  7. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

Reviews

No rating value

Active Filters

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.