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Merck

T8656

Sigma-Aldrich

Thioharnstoff

ACS reagent, ≥99.0%

Synonym(e):

Sulfocarbamid, Thiocarbamid

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About This Item

Lineare Formel:
NH2CSNH2
CAS-Nummer:
Molekulargewicht:
76.12
Beilstein:
605327
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.21

Qualität

ACS reagent

Qualitätsniveau

Assay

≥99.0%

Glührückstand

≤0.1% (as SO4)

Verlust

≤0.5% loss on drying, 105°C, 2h

mp (Schmelzpunkt)

170-176 °C (lit.)
174-177 °C

Löslichkeit

H2O: passes test

SMILES String

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChIKey

UMGDCJDMYOKAJW-UHFFFAOYSA-N

Angaben zum Gen

mouse ... Ephx2(13850)

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Allgemeine Beschreibung

Thiourea is an analogue of urea containing sulphur.

Anwendung

Thiourea has been used:
  • as a component of lysis buffer for liver tissue homogenization
  • in 2-D sample buffer for two-dimensional in-gel protein tyrosine phosphatases (PTP) assay
  • in rehydration buffer for protein extraction

Chaotropisches Reagens; stark denaturierend. Erhöht die Löslichkeit und die Ausbeute von Proteinen

Biochem./physiol. Wirkung

Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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International Journal of ChemTech Research, 4(2), 609-617 (2012)
Investigation of protein-tyrosine phosphatases by in-gel assays.
Markova B, et al.
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