92826

(2RS)-2-Hydroxyadipinsäure Dinatriumsalz

analytical standard

• Synonym(e): α-Hydroxyadipinsäure, 2-Hydroxyhexandisäure, Dinatrium-(2RS)-2-hydroxyadipat
• Empirische Formel (Hill-System): C₆H₈Na₂O₅
• Molekulargewicht: 206.10
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329770177
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Assay: ≥94.0% (GC)
• Haltbarkeit: limited shelf life, expiry date on the label
• Anwendung(en): clinical testing
• Format: neat

Beschreibung

Biochem./physiol. Wirkung

2-Hydroxyadipic acid is a hydroxy-dicarboxylic acid formed by the reduction of 2-ketoadipic acid. Deficiency of 2-ketoadipic dehydrogenase causes 2-ketoadipic academia, a condition characterized by accumulation and excretion of 2-hydroxyadipic acid. A method involving derivatization and combined gas chromatography-mass spectrometry has been recently developed to separate the enantiomers of 3-hydroxyadipic acid. It has been shown that 3-hydroxyadipic acid excreted in urine consists of at least 95% of the L-enantiomer. This finding supports the hypothesis that dicarboxylic acids are degraded by ordinary beta-oxidation, and indicates that adipic acid may be converted into succinic acid.

Hinweis zur Analyse

may contain ethanol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable