131164

Indigokarmin

certified by the Biological Stain Commission, Dye content 85 %

• Synonym(e): Indigo-5,5′-disulfonsäure Dinatriumsalz, Säureblau 74
• Empirische Formel (Hill-System): C₁₆H₈N₂Na₂O₈S₂
• CAS-Nummer: 860-22-0
• Molekulargewicht: 466.35
• Farbindexnummer: 73015
• Beilstein: 4103904
• EG-Nummer: 212-728-8
• MDL-Nummer: MFCD00005723
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 24847997
• NACRES: NA.47

Eigenschaften

• Qualität: certified by the Biological Stain Commission
• Qualitätsniveau: 200
• Assay: >85.0% (HPLC)
• Form: solid
• Zusammensetzung: Dye content, 85%
• Farbe: dark blue to very dark blue
• pH-Wert: 3.87 (30 °C, 7.14 g/L)
• mp (Schmelzpunkt): ≥340 °C
• Dichte: 0.71 g/cm³ at 29 °C
• λmax: 608 nm
• εmax: 20,000 at 250-256 nm in water at 0.01 g/L; 29500 at 284-290 nm in water at 0.01 g/L
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: room temp
• SMILES String: [Na+].[Na+].[O-]S(=O)(=O)c1ccc2NC(\C(=O)c2c1)=C3\Nc4ccc(cc4C3=O)S([O-])(=O)=O
• InChI: 1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2/b14-13+;;
• InChIKey: KHLVKKOJDHCJMG-QDBORUFSSA-L

Beschreibung

Anwendung

Indigo carmine has been used to investigate its effects on ozone production by neutrophils.

Biochem./physiol. Wirkung

Indigo Carmine (IC), commonly known as acid blue 74 or food blue 1 or FD and C blue 2 is a blue synthetic dye. It is used as a redox indicator in analytical chemistry and as a microscopic stain in biology. IC is also employed as a photometric detector. IC is a highly toxic indigoid dye and is associated with various health hazards such as irritation to the gastrointestinal tract leading to nausea, vomiting, and diarrhea and irritation in the respiratory tract leading to coughing and shortness of breath. IC exposure might also cause skin and eye irritations to humans. IC dye spray is used for the diagnosis of dysplasia in ulcerative colitis and is considered to be a simple, feasible, and safe method.

Eignung

Verwendet als Kollagen-Färbemittel und in Verfahren mit roten Kernfärbemitteln.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317
• P-Sätze: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Gefahreneinstufungen: Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves