1.06346

Natriumdihydrogenphosphat-Monohydrat

for analysis EMSURE^® ACS,Reag. Ph Eur

• Synonym(e): Natriumphosphat Monohydrat, Mononatrium-phosphat, Natriumdihydrogenphosphat Monohydrat
• Lineare Formel: NaH₂PO₄ · H₂O
• CAS-Nummer: 10049-21-5
• Molekulargewicht: 137.99
• MDL-Nummer: MFCD00149208
• UNSPSC-Code: 12352302
• EG-Index-Nummer: 231-449-2
• NACRES: NA.21

Eigenschaften

• Qualität: ACS reagent
• Qualitätsniveau: 300
• Agentur: reag. Ph. Eur.
• Produktlinie: EMSURE^®
• Assay: 99.0-102.0% (alkalimetric)
• Form: crystals
• Wirksamkeit: >2000 mg/kg LD₅₀, oral (Rat); >7940 mg/kg LD₅₀, skin (Rabbit)
• Verunreinigungen: ≤0.01% Insoluble matter
• pH-Wert: 4.1-4.5 (25 °C, 50 g/L in H₂O)
• Löslichkeit: 850 g/L
• Dichte: 2.04 g/cm³ at 20 °C
• Schüttdichte: 880 kg/m³
• Anionenspuren: chloride (Cl^-): ≤0.0005%; sulfate (SO₄^2-): ≤0.003%
• Kationenspuren: Ca: ≤0.005%; Fe: ≤0.0005%; K: ≤0.005%; N: ≤0.001%; heavy metals: ≤0.0005%
• UV-Absorption: λ: 280 nm A_max: ≤0.05
• Lagertemp.: 2-30°C
• SMILES String: [Na+].[H]O[H].OP(O)([O-])=O
• InChI: 1S/Na.H3O4P.H2O/c;1-5(2,3)4;/h;(H3,1,2,3,4);1H2/q+1;;/p-1
• InChIKey: BBMHARZCALWXSL-UHFFFAOYSA-M

Beschreibung

Anwendung

• Development of a multiparticulate drug delivery system for in situ amorphisation.: This study explores the use of sodium dihydrogen phosphate monohydrate in developing a multiparticulate drug delivery system. The research highlights the compound′s role in achieving in situ amorphisation, enhancing drug solubility and bioavailability (Holm TP et al., 2022).


• Metabolomic characterization of rhubarb species by capillary electrophoresis and ultra-high-pressure liquid chromatography.: Sodium dihydrogen phosphate monohydrate is utilized in the buffer system for capillary electrophoresis and UHPLC, aiding in the metabolomic analysis of rhubarb species. This research underscores its importance in improving separation efficiency and resolution in analytical methods (Tseng YJ et al., 2013).

Verlinkung

Ersetzt: SX0709; SX0709-5; SX0710; SX0710-1; SX0710-3; SX0710-5; SX0710-20

Hinweis zur Analyse

Gehalt (alkalimetrisch): 99,0 - 102,0 %
Unlösliche Anteile: ≤ 0,01 %
pH-Wert (5 %; Wasser, 25 °C): 4,1 - 4,5
UV-Absorption (280 nm; 1 mol/l; 1 cm; Wasser): ≤ 0,05
Chlorid (Cl): ≤ 0,0005 %
Sulfat (SO₄): ≤ 0,003 %
Gesamtstickstoff (N): ≤ 0,001 %
Schwermetalle (ACS): ≤ 0,0005 %
Ca (Calcium): ≤ 0,005 %
Fe (Eisen): ≤ 0,0005 %
K (Kalium): ≤ 0,005 %
Entspricht ACS, Reag. Ph Eur

Rechtliche Hinweise

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable