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Sigma-Aldrich

Anti-Endostatin Antibody, clone 1837.46

clone 1837.46, Upstate®, from mouse

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200 μL
CHF 461.00

CHF 461.00


Voraussichtliches Versanddatum16. April 2025


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200 μL
CHF 461.00

About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

CHF 461.00


Voraussichtliches Versanddatum16. April 2025


Bulk-Bestellung anfordern

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified antibody

Antikörper-Produkttyp

primary antibodies

Klon

1837.46, monoclonal

Speziesreaktivität

mouse, human

Hersteller/Markenname

Upstate®

Methode(n)

immunohistochemistry: suitable
western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

mouse ... Col18A1(12822)

Spezifität

endostatin

Immunogen

Full-length recombinant murine endostatin

Anwendung

Research Category
Zellstruktur
Research Sub Category
ECM-Proteine
Anti-Endostatin Antibody, clone 1837.46 is an antibody against Endostatin for use in WB, IH.

Qualität

routinely evaluated by immunoblot on 3T3 cell lysates

Zielbeschreibung

Recognizes endostatin, Mr 22kDa An unidentified protein is also weakly detected at Mr 54kDa

Physikalische Form

Thiophilic chromatography
50mM sodium phosphate, pH 8.0, 0.05% sodium azide, before the addition of glycerol to 30%
Format: Purified

Lagerung und Haltbarkeit

2 years at -20°C

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

B V Sauter et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(9), 4802-4807 (2000-04-12)
Inhibition of angiogenesis has been shown to be an effective strategy in cancer therapy in mice. However, its widespread application has been hampered by difficulties in the large-scale production of the antiangiogenic proteins. This limitation may be resolved by in
M C Cichy et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 42(12), 1150-1155 (2009-11-07)
Acute renal failure (ARF) is a frequent complication of Gram-negative sepsis, with a high risk of mortality. Lipopolysaccharide (LPS)-induced ARF is associated with hemodynamic changes that are strongly influenced by the overproduction of nitric oxide (NO) through the cytokine-mediated up-regulation
H M Strik et al.
Cancer, 91(5), 1013-1019 (2001-03-17)
Endostatin is a potent inhibitor of endothelial cell proliferation, angiogenesis, and tumor growth. Its occurrence and localization has not yet been examined in human brain tumors. The authors report the production of a monoclonal antibody and detection of endostatin in
M Dhanabal et al.
The Journal of biological chemistry, 274(17), 11721-11726 (1999-04-17)
Endostatin, a carboxyl-terminal fragment of collagen XVIII, has been shown to regress tumors in mice. In this study, we have analyzed the mechanism of endostatin action on endothelial cells and nonendothelial cells. Endostatin treatment of cow pulmonary artery endothelial cells
Induction of the RNA regulator LIN28A is required for the growth and pathogenesis of RESTless breast tumors.
Gunsalus, KT; Wagoner, MP; Meyer, K; Potter, WB; Schoenike, B; Kim, S; Alexander et al.
Cancer Research null

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