855776C

19:0 Lyso PC

Avanti Research^™ - A Croda Brand 855776C

• Synonym(e): 1-nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine
• Empirische Formel (Hill-System): C₂₇H₅₆NO₇P
• CAS-Nummer: 108273-88-7
• Molekulargewicht: 537.71
• MDL-Nummer: MFCD00672604
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Assay: >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
• Form: liquid
• Verpackung: pkg of 1 × 2.5 mL (855776C-25mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 855776C
• Konzentration: 10 mg/mL (855776C-25mg)
• Versandbedingung: dry ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid secreted on pathological response.[1] It has a choline group at its polar head.[2]

Anwendung

19:0 Lyso PC has been used for the quantification of lysophosphatidylcholine (LPC) in microsomes by mass spectrometry.[3] It has also been used for plasma lipidome analysis of cows.[4]

Biochem./physiol. Wirkung

Lysophosphatidylcholine (LPC) modifies various biological functions in different cell-types, like endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC stimulates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.[1]

Verpackung

5 mL Clear Glass Sealed Ampule (855776C-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• P-Sätze: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Zielorgane: Central nervous system, Liver,Kidney
• WGK: WGK 3