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P49007

Sigma-Aldrich

Piperin

≥97%

Synonym(e):

1-Piperoyl-piperidin

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About This Item

Empirische Formel (Hill-System):
C17H19NO3
CAS-Nummer:
94-62-2
Molekulargewicht:
285.34
Beilstein:
90741
EG-Nummer:
202-348-0
MDL-Nummer:
MFCD00005839
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24898568
NACRES:
NA.22

Qualitätsniveau

100

Assay

≥97%

Form

crystalline
powder, crystals or chunks
solid

mp (Schmelzpunkt)

131-135 °C (lit.)

SMILES String

O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3

InChI

1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+

InChIKey

MXXWOMGUGJBKIW-YPCIICBESA-N

Angaben zum Gen

human ... CYP3A4(1576)

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Anwendung

Reactant for synthesis of:
  • Dimeric amide alkaloids
  • Piperoyl-amino acid conjugates used for antileishmanial activity
  • Piperine derived amides with TRPV1 activity
  • Piperine analogues as S. aureus NorA efflux pump inhibitors
  • Bioactive conjugates of curcumin with antimicrobial and antiproliferative properties
  • Piperine derivatives for use as trypanocidal agents

Piktogramme

Exclamation markEnvironment
GHS07,GHS09

Signalwort

Warning

H-Sätze

H302,H411

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Chronic 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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WWL229 ≥98% (HPLC)

Sigma-Aldrich

SML1180

WWL229

Piperlongumine ≥97% (HPLC)

Sigma-Aldrich

SML0221

Piperlongumine

Pipernonaline ≥95% (LC/MS-ELSD)

Sigma-Aldrich

SMB00093

Pipernonaline

Curcumin from Curcuma longa (Turmeric), powder

Sigma-Aldrich

C1386

Curcumin

Piperolein A ≥90% (LC/MS-UV)

Sigma-Aldrich

SMB00543

Piperolein A

Curcumin ≥94% (curcuminoid content), ≥80% (Curcumin)

Sigma-Aldrich

C7727

Curcumin

Jiu-Wang Yu et al.
Molecular diversity, 25(1), 233-248 (2020-03-05)
Piperine is the main active component of Piper longum L., which is also the main component of anti-sciatica Mongolian medicine Naru Sanwei pill. It has many pharmacological activities such as anti-inflammatory and immune regulation. This paper aims to preliminarily explore
V. R. S. Rao, et al.,
Tetrahedron, 67, 1885-1892 (2011)
Welisson da Silva Ferreira et al.
Bioorganic & medicinal chemistry, 16(6), 2984-2991 (2008-01-30)
We herein describe the synthesis and characterization of nine new 1,3,4-thiadiazolium-2-phenylamine chlorides derived from natural piperine. We evaluate their toxic effects against the different evolutive forms of Trypanosoma cruzi, and the host cell (murine macrophages). The results obtained show that
Janine Zaugg et al.
Journal of natural products, 73(2), 185-191 (2010-01-21)
A plant extract library was screened for GABA(A) receptor activity making use of a two-microelectrode voltage clamp assay on Xenopus laevis oocytes. An ethyl acetate extract of black pepper fruits [Piper nigrum L. (Piperaceae) 100 microg/mL] potentiated GABA-induced chloride currents
Shiv K Dubey et al.
European journal of medicinal chemistry, 43(9), 1837-1846 (2008-01-19)
The monoesters of curcumin, a symmetric diphenol with valine and glycine have been prepared by a novel solid phase synthesis and its diesters with valine, glutamic acid and demethylenated piperic acid have been prepared by solution phase method. The assessment
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