N17734

6-Nitroindolin

97%

• Synonym(e): 6-Nitro-2,3-dihydroindole, NSC 80658
• Empirische Formel (Hill-System): C₈H₈N₂O₂
• CAS-Nummer: 19727-83-4
• Molekulargewicht: 164.16
• EG-Nummer: 243-257-6
• MDL-Nummer: MFCD00005710
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24897527
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Form: powder
• mp (Schmelzpunkt): 67-69 °C (lit.)
• SMILES String: [O-][N+](=O)c1ccc2CCNc2c1
• InChI: 1S/C8H8N2O2/c11-10(12)7-2-1-6-3-4-9-8(6)5-7/h1-2,5,9H,3-4H2
• InChIKey: LTNYDSMDSLOMSM-UHFFFAOYSA-N

Beschreibung

Anwendung

• Reactant for preparation of 2-[(2,3-Dihydro-1H-indol-1-yl)methyl]melatonin analogs as novel MT2-selective melatonin receptor antagonists
• Reactant for synthesis of isoindigo and azaisoindigo glycosides as anticancer agents
• Reactant for preparation of arylfurancarboxamides with Nav1.8 voltage-gated Na channel blocking/analgesic activities
• Reactant for preparation of bicyclic benzamides as 5-HT1 receptor agonists
• Reactant for preparation of antiarrhythmic benzopyrans
• Reactant for preparation of 5-HT2C/2B receptor antagonists

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves