L040082

Cap A

• UNSPSC-Code: 12352200
• NACRES: NA.21

Eigenschaften

• Typ: for DNA synthesis
• Qualitätsniveau: 200
• Produktlinie: Proligo Reagents

Beschreibung

Angaben zur Herstellung

Acetic Anhydride / Tetrahydrofurane 9.1/90.9 (v/v)

Sonstige Hinweise

Cap A solution, containing acetic anhydride and tetrahydrofuran (THF), is used after the phosphoramidite reaction/coupling step. This solution aborts chains bearing unreacted 5′hydroxyl groups due to failure of reaction with activated phosphoramidite (typically, 1 to 2% of growing oligonucleotide chains in each synthesis cycle). These unreacted 5′hydroxyl groups are capped with an acetyl group and thus rendered unreactive for subsequent synthesis steps.

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08,GHS05
• Signalwort: Danger
• H-Sätze: H225,H302,H315,H318,H331,H335,H336,H351
• P-Sätze: P210 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Zusätzliche Gefahrenhinweise: EUH019
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 6.1 °F
• Flammpunkt (°C): -14.4 °C