B29806

1-Benzyl-4-piperidon

99%

• Synonym(e): 1-Benzyl-4-oxo-piperidin
• Empirische Formel (Hill-System): C₁₂H₁₅NO
• CAS-Nummer: 3612-20-2
• Molekulargewicht: 189.25
• Beilstein: 128556
• EG-Nummer: 222-782-4
• MDL-Nummer: MFCD00006192
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24891676
• NACRES: NA.22

Eigenschaften

• Assay: 99%
• Form: liquid
• Brechungsindex: n20/D 1.541 (lit.)
• bp: 134 °C/7 mmHg (lit.)
• Dichte: 1.021 g/mL at 25 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: O=C1CCN(CC1)Cc2ccccc2
• InChI: 1S/C12H15NO/c14-12-6-8-13(9-7-12)10-11-4-2-1-3-5-11/h1-5H,6-10H2
• InChIKey: SJZKULRDWHPHGG-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

1-Benzyl-4-piperidone serves as a versatile heterocyclic building block in the synthesis of pharmaceutical compounds.

Anwendung

1-Benzyl-4-piperidone is generally used as a building block in the synthesis of various medicinal compounds. Applications include the synthesis of:

• Spirocyclic furopyridines as haloperidol-sensitive σ receptor ligands.
• Multi-target-directed donepezil + propargylamine + 8-hydroxyquinoline (DPH) hybrids for the treatment of Alzheimer′s disease.
• Spiropiperidine iminohydantoin aspartyl protease inhibitors.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319
• P-Sätze: P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 159.8 °F
• Flammpunkt (°C): 71 °C
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter