664081

N-Benzylpiperidin-4-Carboxaldehyd

95%

• Synonym(e): 1-(Phenylmethyl)-4-piperidinecarboxaldehyde, 1-Benzyl-4-formylpiperidine, 1-Benzylisonipecotaldehyde
• Empirische Formel (Hill-System): C₁₃H₁₇NO
• CAS-Nummer: 22065-85-6
• Molekulargewicht: 203.28
• EG-Nummer: 244-757-7
• MDL-Nummer: MFCD02258902
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24884678
• NACRES: NA.22

Eigenschaften

• Assay: 95%
• Brechungsindex: n20/D 1.537
• bp: 315.4 °C/760 mmHg
• Dichte: 1.026 g/mL at 25 °C
• Funktionelle Gruppe: aldehyde; phenyl
• SMILES String: O=CC1CCN(CC1)Cc2ccccc2
• InChI: 1S/C13H17NO/c15-11-13-6-8-14(9-7-13)10-12-4-2-1-3-5-12/h1-5,11,13H,6-10H2
• InChIKey: SGIBOXBBPQRZDM-UHFFFAOYSA-N

Beschreibung

Anwendung

Building block used in a synthesis of donepezil, a reversible inhibitor of acetylcholinesterase.[1]

Reactant for:

• Stereospecific allylic alkylation
• Reactions of Grignard reagents with carbonyl compounds
• Fluorodenitrations and nitrodehalogenations for labeled PET ligands and fluoropharmaceuticals
• Selective α1 receptor antagonists

Reactant for synthesis of:

• Donepezil
• MCH-R1 antagonists

Sicherheitshinweise

• Piktogramme: GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H301,H318
• P-Sätze: P280 - P301 + P310 + P330 - P305 + P351 + P338 + P310
• Gefahreneinstufungen: Acute Tox. 3 Oral - Eye Dam. 1
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): >230.0 °F - closed cup
• Flammpunkt (°C): > 110 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter