647241

(R)-(−)-1-Methyl-3-Pyrrolidinol

97%

• Synonym(e): (R)-(−)-3-Hydroxy-N-methylpyrrolidin
• Empirische Formel (Hill-System): C₅H₁₁NO
• CAS-Nummer: 104641-60-3
• Molekulargewicht: 101.15
• MDL-Nummer: MFCD03788747
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24883519
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Optische Aktivität: [α]20/D -7°, c = 1% in chloroform
• Brechungsindex: n20/D 1.4640 (lit.)
• bp: 50-52 °C/1 mmHg (lit.)
• Dichte: 0.921 g/mL at 25 °C (lit.)
• SMILES String: CN1CC[C@@H](O)C1
• InChI: 1S/C5H11NO/c1-6-3-2-5(7)4-6/h5,7H,2-4H2,1H3/t5-/m1/s1
• InChIKey: FLVFPAIGVBQGET-RXMQYKEDSA-N

Beschreibung

Anwendung

Reactant for:

• Asymmetric synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors
• Preparation of diaryl acylaminopyrimidines as adenosine A2A antagonists
• Synthesis of analogs of istaroxime, a potent inhibitor of Na⁺,K⁺-ATPase
• Synthesis of pharmacologically active stereoisomers of N-substituted soft anticholinergics

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 158.0 °F
• Flammpunkt (°C): 70 °C
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter