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4-Nitropyrazol-3-carbonsäure
98%
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About This Item
Empirische Formel (Hill-System):
C4H3N3O4
CAS-Nummer:
Molekulargewicht:
157.08
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
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Assay
98%
mp (Schmelzpunkt)
223-225 °C (dec.) (lit.)
SMILES String
OC(=O)c1n[nH]cc1[N+]([O-])=O
InChI
1S/C4H3N3O4/c8-4(9)3-2(7(10)11)1-5-6-3/h1H,(H,5,6)(H,8,9)
InChIKey
ZMAXXOYJWZZQBK-UHFFFAOYSA-N
Allgemeine Beschreibung
Effects of this pyrrazole on blood flow and its palladium hydrogenation have been studied.
Anwendung
4-Nitro-3-pyrazolecarboxylic acid may be used as a starting reagent for the synthesis of library of pyrazole derivatives, potential A3 adenosine receptor (A3AR) antagonists.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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SERS investigation on 4-nitro-3-pyrazolecarboxylic acid adsorbed on palladium-doped silver nanoparticles.
Pergolese B, et al.
Vibrational Spectroscopy, 48(1), 107-112 (2008)
Jing Wei et al.
Neurochemistry international, 55(7), 637-642 (2009-06-23)
Adenosine is known to act as a neuromodulator by suppressing synaptic transmission in the central and peripheral nervous system. A(3) adenosine receptor (A(3)AR) antagonists were recently considered as potential drugs for the treatment of cardiac ischemia and inflammation diseases. To
Hydrogenation on Granular Palladium-containing Catalysts: II. Hydrogenation of Nitroheterocyclic Compounds
Russ. J. Org. Chem., 38, 269-271 (2002)
Bo Xuan et al.
Acta pharmacologica Sinica, 23(8), 705-712 (2002-07-31)
Effects of C-nitropyrazoles and C-nitroazoles on ocular blood flow and retinal function recovery after ischemia have been studied. The compounds were tested on ocular blood flow of ocular hypertensive (40 mmHg) rabbit eyes with colored microsphere technique. They were also
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