394963

N,N-Dimethylformamiddimethylacetal

for GC derivatization, LiChropur^™

• Synonym(e): 1,1-Dimethoxy-N,N-dimethylmethylamin, 1,1-Dimethoxytrimethylamin
• Lineare Formel: (CH₃)₂NCH(OCH₃)₂
• CAS-Nummer: 4637-24-5
• Molekulargewicht: 119.16
• Beilstein: 506020
• EG-Nummer: 225-063-3
• MDL-Nummer: MFCD00008482
• UNSPSC-Code: 12000000
• PubChem Substanz-ID: 24864631
• NACRES: NA.22

Eigenschaften

• Qualität: for GC derivatization; LiChropur^™
• Assay: >95%
• Form: liquid
• Eignung der Reaktion: reagent type: derivatization reagent; reaction type: Acylations; reagent type: derivatization reagent; reaction type: Esterifications
• Methode(n): gas chromatography (GC): suitable
• Brechungsindex: n20/D 1.396 (lit.)
• bp: 102-103 °C/720 mmHg (lit.)
• Dichte: 0.897 g/mL at 25 °C (lit.)
• SMILES String: COC(OC)N(C)C
• InChI: 1S/C5H13NO2/c1-6(2)5(7-3)8-4/h5H,1-4H3
• InChIKey: ZSXGLVDWWRXATF-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Esterate M (N,N-Dimethylformamide dimethyl acetal, DMFDMA) is an methylating reagent. It has been used in methyl esterification of carboxylic acid and also in one-step derivatization of amino acids into N,N-Dimethylaminomethylene methyl esters.

Anwendung

Für die Katalyse der Kopplung von Epoxiden mit Kohlendioxid unter lösungsmittelfreien Bedingungen zu cyclischen Carbonaten.

Zur Herstellung von Formamidin-Derivaten, als Syntheseintermediate

It may be used in methylation of heterocyclic compounds which contains SH, NH, OH groups such as benzimidazole, naphth[2,3-c]imidazole, imidazo[4,5-c]-pyridine, purine, pyridine, pyrimidine, pyridazine and s-triazolo[4,3-b]pyridazine. It was used as derivatizing agent in a study to determine cocaine and benzoyl ecgonine in urine using GC with on-column alkylation.

Suitable for the derivatization of primary sulfonamides and trifluoroacetic acid.

Sonstige Hinweise

Reagent for n-dimethylaminomethylene and methyl esters.

Rechtliche Hinweise

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H225,H317,H318,H332
• P-Sätze: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Sens. 1
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 42.8 °F
• Flammpunkt (°C): 6 °C
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter