387800

5-Chlor-2,4,6-trifluorpyrimidin

99%

• Empirische Formel (Hill-System): C₄ClF₃N₂
• CAS-Nummer: 697-83-6
• Molekulargewicht: 168.50
• Beilstein: 610168
• EG-Nummer: 211-807-4
• MDL-Nummer: MFCD00191933
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24864189
• NACRES: NA.22

Eigenschaften

• Assay: 99%
• Brechungsindex: n20/D 1.439 (lit.)
• bp: 116 °C (lit.)
• Dichte: 1.626 g/mL at 25 °C (lit.)
• SMILES String: Fc1nc(F)c(Cl)c(F)n1
• InChI: 1S/C4ClF3N2/c5-1-2(6)9-4(8)10-3(1)7
• InChIKey: GOYNRDSJTYLXBU-UHFFFAOYSA-N

Beschreibung

Anwendung

5-Chloro-2,4,6-trifluoropyrimidine can be used as a starting material to synthesize:

• 4-azido-5-chloro-2,6-difluoro-pyrimidine by azidation reaction with sodium azide.
• 5-chloro triphenoxy pyrimidine by reacting with tetraphenoxysilane in the presence of tetra butyl ammonium fluoride (TBAF).
• 5-chloro-2,6-difluoropyrimidin-4-amine, and 5-chloro-4,6-difluoropyrimidin-2-amine (9:1 ratio) by reacting with ammonia.
• 5-Chloro-N,N -diethyl-2,6-dipyrimidin-4-amine, by treating with diethylamine and DIPEA.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 230.0 °F - closed cup
• Flammpunkt (°C): 110 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter