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333786

Sigma-Aldrich

3-(3,4-Dihydroxyphenyl-2,5,6-d3)-L-alanin

≥98 atom % D, ≥98% (CP)

Synonym(e):

L-Dopa-(phenyl-d3)

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250 MG
CHF 134.00
1 G
CHF 298.00

CHF 134.00


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250 MG
CHF 134.00
1 G
CHF 298.00

About This Item

Lineare Formel:
(HO)2C6D3CH2CH(NH2)CO2H
CAS-Nummer:
Molekulargewicht:
200.21
MDL-Nummer:
UNSPSC-Code:
12352209
PubChem Substanz-ID:
NACRES:
NA.12

CHF 134.00


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Isotopenreinheit

≥98 atom % D

Qualitätsniveau

Assay

≥98% (CP)

Form

powder

Optische Aktivität

[α]27/D −11.5°, c = 5 in 1 M HCl

Methode(n)

mass spectrometry (MS): suitable

mp (Schmelzpunkt)

292 °C (dec.) (lit.)

Massenverschiebung

M+3

Lagertemp.

2-8°C

SMILES String

[2H]c1c([2H])c(C[C@H](N)C(O)=O)c([2H])c(O)c1O

InChI

1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1/i1D,2D,4D

InChIKey

WTDRDQBEARUVNC-UOCCHMHCSA-N

Verwandte Kategorien

Allgemeine Beschreibung

L-Dopa-(phenyl-d3) is an isotopic analogue of 3-(3,4-Dihydroxyphenyl)-L-alanine amino acid.

Anwendung

L-Dopa-(phenyl-d3) or (3-(3,4-dihydroxyphenyl-2,5,6-d3)-L-alanine) can be used as an internal standard for the quantification of methyldopa in human plasma by LC-MS-MS based method.[1]
L-Dopa-(phenyl-d3) can be used as an internal standard.

Verpackung

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Die Dokumentenbibliothek aufrufen

Jeong-Ook Lee et al.
Journal of ginseng research, 42(3), 389-399 (2018-07-10)
The antioxidant effects of Panax ginseng have been reported in several articles; however, little is known about the antimelanogenesis effect, skin-protective effect, and cellular mechanism of Panax ginseng, especially of P. ginseng calyx. To understand how an ethanol extract of
Dario Breitel et al.
Metabolic engineering, 65, 185-196 (2020-11-27)
L-DOPA, also known as Levodopa or L-3,4-dihydroxyphenylalanine, is a non-standard amino acid, and the gold standard drug for the treatment for Parkinson's Disease (PD). Recently, a gene encoding the enzyme that is responsible for its synthesis, as a precursor of
Celso H Oliveira et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 768(2), 341-348 (2002-03-13)
A method based on LC-MS-MS is described for the determination of methyldopa in human plasma using dopa-phenyl-D3 as the internal standard. The method has a chromatographic run time of 5.5 min and was linear in the range of 20-5000 ng/ml.
Quantification of methyldopa in human plasma by high-performance liquid chromatography?electrospray tandem mass spectrometry: Application to a bioequivalence study
Oliveira CH, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 2(768), 341-348 (2002)
Glauber de S Araujo et al.
PloS one, 7(1), e29561-e29561 (2012-01-19)
Capsule production is common among bacterial species, but relatively rare in eukaryotic microorganisms. Members of the fungal Cryptococcus genus are known to produce capsules, which are major determinants of virulence in the highly pathogenic species Cryptococcus neoformans and Cryptococcus gattii.

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