287644

(1R,2R)-(−)-Pseudoephedrin

98%

• Synonym(e): α-(1-Methylaminoethyl)-benzylalkohol, (−)-ψ-Ephedrin, (−)-Pseudoephedrin, (1R,2R)-(−)-2-(Methylamino)-1-phenylpropanol, l-Pseudoephedrin
• Lineare Formel: C₆H₅CH[CH(NHCH₃)CH₃]OH
• CAS-Nummer: 321-97-1
• Molekulargewicht: 165.23
• Beilstein: 2803417
• EG-Nummer: 206-292-8
• MDL-Nummer: MFCD00002203
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 24857283
• NACRES: NA.22

Eigenschaften

• Assay: 98%
• Form: solid
• Optische Aktivität: [α]20/D −51°, c = 0.6 in ethanol
• mp (Schmelzpunkt): 118-120 °C (lit.)
• SMILES String: CN[C@H](C)[C@H](O)c1ccccc1
• InChI: 1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10+/m1/s1
• InChIKey: KWGRBVOPPLSCSI-SCZZXKLOSA-N

Beschreibung

Allgemeine Beschreibung

(1R,2R)-(-)-Pseudoephedrine is an enantiomer of ephedrine mainly used as a chiral auxiliary for asymmetric synthesis.

Anwendung

(1R,2R)-(-)-Pseudoephedrine may be used in the preparation of chiral relay ligands, which can catalyze the addition of diethylzinc to aldehydes leading to the corresponding secondary alcohol. The immobilization of pseudoephedrine on Merrifield resin forms a chiral linker, which may be used for the asymmetric alkylation of amides via solid-phase approach.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H302,H314,H317,H336
• P-Sätze: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves