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Merck

153516

Sigma-Aldrich

Lactobionsäure

97% (TLC)

Synonym(e):

4-O-β-D-Galactopyranosyl-D-gluconsäure

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25 G
CHF 136.00
100 G
CHF 389.00

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25 G
CHF 136.00
100 G
CHF 389.00

About This Item

Empirische Formel (Hill-System):
C12H22O12
CAS-Nummer:
Molekulargewicht:
358.30
Beilstein:
95054
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352201
PubChem Substanz-ID:
NACRES:
NA.25

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Biologische Quelle

synthetic

Qualitätsniveau

Assay

97% (TLC)

Form

powder or crystals

Optische Aktivität

[α]20/D +25°, c = 10 in H2O

Farbe

white

mp (Schmelzpunkt)

113-118 °C (lit.)

Löslichkeit

5%, clear, colorless

Lagertemp.

room temp

SMILES String

OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C(O)=O

InChI

1S/C12H22O12/c13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h3-10,12-20H,1-2H2,(H,21,22)/t3-,4-,5+,6+,7-,8-,9-,10-,12+/m1/s1

InChIKey

JYTUSYBCFIZPBE-AMTLMPIISA-N

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Anwendung

Lactobionsäure ist eine α-Hydroxysäure (AHA) mit antioxidativer Aktivität und wird für die Entwicklung von Hautkosmetik verwendet. Lactobionsäure wird für die Entwicklung von Systemen für die gezielte Wirkstoffabgabe – etwa Mikrokapseln – genutzt.

Sonstige Hinweise

Für einen umfassenden Überblick über unser vielfältiges Angebot an Disacchariden für Ihre Forschung empfehlen wir Ihnen den Besuch unserer Seite zur Kategorie Kohlenhydrate.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Barbara A Green et al.
Clinics in dermatology, 27(5), 495-501 (2009-08-22)
The hydroxyacids are represented by the alpha-hydroxyacids, beta-hydroxyacids, polyhydroxy acids, and bionic acids. Together, these ingredients form a class of compounds with unparalleled benefits to the skin and unprecedented usage in the cosmeceutical market in cosmetic and therapeutic formulations alike.
Chang-Moon Lee et al.
Magnetic resonance in medicine, 62(6), 1440-1446 (2009-10-28)
Hepatocyte-specific targeting agents are useful for evaluation of the hepatocytic function and the monitoring of disease progress. Superparamagnetic iron oxide nanoparticles (SPION) bearing terminal galactose groups exhibit a high affinity for the asialoglycoprotein receptor on the hepatocyte surface. In this
Jing Zhang et al.
Acta biomaterialia, 7(4), 1665-1673 (2010-12-07)
This paper demonstrates a general approach for fabrication of lactobionic chitosan microcapsules using layer-by-layer assembly via click chemistry. Chitosan was selectively modified with either azide (CHI-Az) or alkyne (CHI-Alk) groups. The growth of the CHI-Az/CHI-Alk click multilayer was studied experimentally
Fang Wu et al.
Molecular pharmaceutics, 6(5), 1506-1517 (2009-07-30)
We aim to define the role of Kupffer cells in intrahepatic antigen presentation, using the selective delivery of antigen to Kupffer cells rather than other populations of liver antigen-presenting cells. To achieve this we developed a novel antigen delivery system
Xuejiao Zhang et al.
Journal of pharmaceutical sciences, 102(1), 145-153 (2012-11-08)
Mixed copolymer nanoparticles (NPs) self-assembled from β-cyclodextrin-grafted hyperbranched polyglycerol (HPG-g-CD) and lactobionic acid (LA)-grafted hyperbranched polyglycerol (HPG-g-LA) were applied as carriers for a hydrophobic antitumor drug, paclitaxel (PTX), achieving hepatocellular carcinoma-targeted delivery. The resulting NPs exhibited high drug loading capacity

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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