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Sigma-Aldrich

Tetramethylthioharnstoff

98%

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About This Item

Lineare Formel:
(CH3)2NCSN(CH3)2
CAS-Nummer:
2782-91-4
Molekulargewicht:
132.23
Beilstein:
1744916
EG-Nummer:
220-488-0
MDL-Nummer:
MFCD00008324
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24847202
NACRES:
NA.22

Assay

98%

Form

solid

bp

245 °C (lit.)

mp (Schmelzpunkt)

75-77 °C (lit.)

Lagertemp.

2-8°C

SMILES String

CN(C)C(=S)N(C)C

InChI

1S/C5H12N2S/c1-6(2)5(8)7(3)4/h1-4H3

InChIKey

MNOILHPDHOHILI-UHFFFAOYSA-N

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Allgemeine Beschreibung

Tetramethylthiourea molecule shows crystallographic two-fold symmetry with weak hydrogen bond packing, which connects the molecules to form layers.

Anwendung

Tetramethylthiourea forms BF3 adduct with tetramethylselenourea.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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Y Usson et al.
Journal of neurocytology, 17(5), 639-648 (1988-10-01)
The proliferation of Schwann cells in the sciatic nerve of chick was studied from day 11 to day 27 of development in control and thyroid-deficient embryos. Hypothyroidism was induced by tetramethylthiourea injection on days 8 and 19 of incubation. The
Allen Mambanda et al.
Dalton transactions (Cambridge, England : 2003), 39(15), 3595-3608 (2010-04-01)
The rate of displacement of the aqua ligands by three neutral nucleophiles (Nu) of different steric demands, namely thiourea (tu), N,N'-dimethylthiourea (dmtu) and N,N,N',N'-tetramethylthiourea (tmtu) and an anionic nucleophile (I(-)) in complexes of the form [{Pt(H(2)O)}(2)(N,N,N',N'-tetrakis(2-pyridylmethyl)-N(CH(2))(n)N](CF(3)SO(3))(4), n = 2 (En);
A Shukla et al.
Cancer research, 61(5), 1791-1795 (2001-03-31)
Crystalline silica has been classified as a group 1 human carcinogen in the lung. However, its mechanisms of action on pulmonary epithelial cells which give rise to lung cancers are unclear. Using a nontransformed alveolar type II epithelial cell line
Jiqin Liu et al.
Molecular immunology, 45(15), 3984-3989 (2008-07-29)
N-Acetylcysteine (NAC) has been widely used as an antioxidant in research, however, it has also been found to reduce the binding of TNF to its receptor independent of its antioxidative role. In this study, we investigated the effect of NAC
Alexius Freyberger et al.
Toxicology, 217(2-3), 169-175 (2005-11-22)
N,N,N',N'-Tetramethylthiourea (TMTU) is a rat goitrogen inducing thyroid hyperplasia, hypertrophy, and tumor formation. Little is known about the exact underlying mechanism of action. As thyroid peroxidase (TPO) and type I iodothyronine deiodinase (ID-I) have been established as targets of goitrogenic
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