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Merck

GABRA6

gamma-aminobutyric acid (GABA) A receptor, alpha 6

Synonyme:
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2559) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(14399) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6
  • Rat(29708) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • dog(489145) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • domestic cat(101093992) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • cow(539194) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • sheep(101117503) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • Horse(100070890) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • naked mole-rat(101720123) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • domestic guinea pig(100720891) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • chicken(395931) gamma-aminobutyric acid (GABA) A receptor, alpha 6

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Gaboxadol -hydrochlorid, solid, ≥98% (HPLC),
Spezies
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Spezies
human
Isoguvacine hydrochloride, solid,
Spezies
human
Piperidine-4-sulfonic acid, ,
Spezies
human
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
Dehydroisoandrosteron-3-Sulfat Natriumsalz Dihydrat, ≥93% (TLC), powder,
Spezies
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Spezies
human
trans-Dehydroandrosteron, ≥99%,
Spezies
human, rat
Midazolam -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Diazepam -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Ro 15-4513, solid,
Spezies
rat, human
Picrotoxin, powder,
Spezies
human
Pregnenolone sulfate sodium salt, ,
Spezies
human
SR-95531, ≥98% (HPLC), powder,
Spezies
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-GABA A Receptor α6 Antibody, Chemicon®, from rabbit,
Speziesreaktivität
rat
Anwendung
immunohistochemistry
western blot
Anti-GABAA Receptor (α6 subunit), Cytosolic Loop antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
rat
Anwendung
western blot
Anti-GABAA Receptor (α6 subunit) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
rat
Anwendung
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
NO-711 hydrochloride, ≥98% (HPLC),
Spezies
human
(±)-Vigabatrin, ,
Spezies
human
2,6-Diisopropylphenol, 97%,
Spezies
human
Topiramat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
Etomidat, >98% (HPLC), powder,
Spezies
human
Flumazenil, >99% (HPLC), solid,
Spezies
rat, human
Carbamazepin, powder,
Spezies
rat, human
2-Brom-2-chlor-1,1,1-trifluorethan, ≥99%,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GABRA6,
Spezies
human