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G019

Sigma-Aldrich

Muscimol hydrobromide

≥98% (HPLC), solid

Synonym(e):

5-Aminomethyl-3-hydroxyisoxazole hydrobromide

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5 MG
CHF 149.00
10 MG
CHF 232.00
25 MG
CHF 384.00
100 MG
CHF 1’540.00

CHF 149.00

Voraussichtliches Versanddatum09. April 2025

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5 MG
CHF 149.00
10 MG
CHF 232.00
25 MG
CHF 384.00
100 MG
CHF 1’540.00

About This Item

Empirische Formel (Hill-System):
C4H6N2O2 · HBr
CAS-Nummer:
18174-72-6
Molekulargewicht:
195.01
MDL-Nummer:
MFCD00055184
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24278168
NACRES:
NA.77

CHF 149.00

Voraussichtliches Versanddatum09. April 2025

Bulk-Bestellung anfordern

Qualitätsniveau

100

Assay

≥98% (HPLC)

Form

solid

Farbe

off-white to tan

Löslichkeit

H2O: >10 mg/mL

Lagertemp.

2-8°C

SMILES String

Br[H].NCc1cc(O)no1

InChI

1S/C4H6N2O2.BrH/c5-2-3-1-4(7)6-8-3;/h1H,2,5H2,(H,6,7);1H

InChIKey

OPZOJWHOZRKYQX-UHFFFAOYSA-N

Angaben zum Gen

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562)

Biochem./physiol. Wirkung

Muscimol hydrobromide is a GABAA receptor agonist.

Leistungsmerkmale und Vorteile

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the GABAA Receptors and GABAC Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

H-Sätze

H301

Gefahreneinstufungen

Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
0000180414
0000152969
0000152969
0000133345
0000133345

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Elina A K Jacobs et al.
Current biology : CB, 30(24), 4944-4955 (2020-10-24)
In many behavioral tasks, cortex enters a desynchronized state where low-frequency fluctuations in population activity are suppressed. The precise behavioral correlates of desynchronization and its global organization are unclear. One hypothesis holds that desynchronization enhances stimulus coding in the relevant
Andrew Miri et al.
Neuron, 95(3), 683-696 (2017-07-25)
Blocking motor cortical output with lesions or pharmacological inactivation has identified movements that require motor cortex. Yet, when and how motor cortex influences muscle activity during movement execution remains unresolved. We addressed this ambiguity using measurement and perturbation of motor
Mohammed Z Ariffin et al.
Frontiers in neuroanatomy, 11, 79-79 (2017-10-03)
Cholinergic mechanisms in supramammillary nucleus (SuM), especially the lateral SuM (lSuM) modulates septo-hippocampal neural activity. The lSuM, as compared to the contiguous medial SuM (mSuM) has relatively dense projections to hippocampus and cingulate cortex (Cg). In the present study, we
Benjamin A Rowland et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(21), 7198-7202 (2014-05-23)
Detecting and locating environmental events are markedly enhanced by the midbrain's ability to integrate visual and auditory cues. Its capacity for multisensory integration develops in cats 1-4 months after birth but only after acquiring extensive visual-auditory experience. However, briefly deactivating
Max F K Happel et al.
PloS one, 12(1), e0169461-e0169461 (2017-01-04)
Robust perception of auditory objects over a large range of sound intensities is a fundamental feature of the auditory system. However, firing characteristics of single neurons across the entire auditory system, like the frequency tuning, can change significantly with stimulus
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