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Merck
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8.55137

Sigma-Aldrich

PAL-NovaSyn TG resin

Novabiochem®

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About This Item

Code UNSPSC :
13111023
Nomenclature NACRES :
NA.22

Niveau de qualité

Gamme de produits

NovaSyn® TG
Novabiochem®

Forme

beads

Capacité de réaction

reaction type: Fmoc solid-phase peptide synthesis

Fabricant/nom de marque

Novabiochem®

Application(s)

peptide synthesis

Groupe fonctionnel

amine

Température de stockage

2-8°C

Description générale

PAL-NovaSyn TG resin consists of Barany′s aminomethyl-dimethoxyphenoxyvaleric acid linker [1] attached to NovaSyn TG resin. The amino group of this linker can be easily acylated under standard coupling conditions. Following peptide assembly, treatment with 95% TFA containing scavengers releases the desired peptide amide. Studies have shown the acid sensitivity of this linker to be around twice that of the Rink amide linker [2]. There is some evidence to suggest that PAL resins give greater yields in microwave assisted synthesis.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Remarque sur l'analyse

Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer metrix is copoly (styrene - 1% DVB), 100 - 200 mesh.

Informations légales

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Articles

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Protocoles

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

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