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B4388

Sigma-Aldrich

2-Bromo-2-chloro-1,1,1-trifluoroethane

≥99%

Synonyme(s) :

Halothane

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About This Item

Formule linéaire :
BrCH(Cl)CF3
Numéro CAS:
151-67-7
Poids moléculaire :
197.38
Numéro Beilstein :
1736947
Numéro CE :
205-796-5
Numéro MDL:
MFCD00009602
Code UNSPSC :
12352202
ID de substance PubChem :
24891772
Nomenclature NACRES :
NA.77

Pression de vapeur

4.5 psi ( 20 °C)

Pureté

≥99%

Forme

liquid

Contient

0.01% thymol as stabilizer

Indice de réfraction

n20/D 1.369 (lit.)

Point d'ébullition

50.2 °C (lit.)

Densité

1.872 g/mL at 25 °C (lit.)

Chaîne SMILES 

FC(F)(F)C(Cl)Br

InChI

1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H

Clé InChI

BCQZXOMGPXTTIC-UHFFFAOYSA-N

Informations sur le gène

human ... ATP5D(513) , GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879) , GLRA1(2741) , GLRB(2743) , GRIA1(2890) , KCNK10(54207) , KCNK18(338567) , KCNK2(3776) , KCNK3(3777) , KCNK9(51305) , KCNN4(3783)

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Application

2-Bromo-2-chloro-1,1,1-trifluoroethane, or halothane, has been used in a study that combined molecular simulations with free energy simulations to study solvation of halothane in polarizable water and methanol. Halothane has also been used in a study to investigate the interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor.

Actions biochimiques/physiologiques

2-Bromo-2-chloro-1,1,1-trifluoroethane is an inhalation anesthetic. In an effect believed to be independent of anesthesia, halothane inhibits the synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step.

Pictogrammes

Health hazardCorrosionExclamation mark
GHS08,GHS05,GHS07

Mention d'avertissement

Danger

Mentions de danger

H315,H318,H335,H360

Classification des risques

Eye Dam. 1 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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