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P7380

Sigma-Aldrich

Purpurogallin

Sigma Grade

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About This Item

Formule empirique (notation de Hill):
C11H8O5
Numéro CAS:
569-77-7
Poids moléculaire :
220.18
Numéro CE :
209-324-9
Numéro MDL:
MFCD00004145
Code UNSPSC :
12171500

Qualité

Sigma Grade

Pf

275 °C (dec.) (lit.)

Température de stockage

−20°C

Chaîne SMILES 

OC1=CC=Cc2cc(O)c(O)c(O)c2C1=O

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Application

Calibration standard for peroxidase assays using pyrogallol as substrate.

Actions biochimiques/physiologiques

Polyphenol antibiotic originally isolated from Quercus nutgall that has antioxidant activity. Competitive inhibitor of epidermal growth factor receptor protein tyrosine kinase activity; inhibitor of xanthine oxidase.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Conseils de prudence

P261 - P305 + P351 + P338

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Code de la classe de stockage

13 - Non Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

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O Nozaki et al.
Journal of bioluminescence and chemiluminescence, 10(3), 151-156 (1995-05-01)
The effects of various boronate compounds, 4-biphenylboronic acid, 4-bromobenzene-boronic acid, trans-4-(3-propionic acid)phenylboronic acid and 4-iodophenylboronic acid, on the horseradish peroxidase (HRP) catalysed chemiluminescent oxidation of pyrogallol and purpurogallin by peroxide were investigated. trans-4-(3-Propionic acid)phenylboronic acid produced a 13.7-fold enhancement in
Akram Jamshidzadeh et al.
Journal of applied toxicology : JAT, 27(4), 322-326 (2007-02-01)
Chloroquine is a synthetic quinoline being used as an antimalaria and antirheumatoid agent. Several cases of hepatotoxicity have been reported with the use of chloroquine. However, the mechanism(s) of its hepatotoxic effect is unknown. The purpose of this study was
Mairtin O'Coinceanainn et al.
Journal of inorganic biochemistry, 96(4), 463-468 (2003-09-19)
Polyphenols are antioxidants, which are known to influence bioavailability of metals in the body. The theaflavins of black tea are important members of this family, which have been sparsely investigated. The complexation of aluminium with purpurogallin (2,3,4,6-tetrahydroxy-5H-benzocyclohepten-5-one) has been investigated
K P Fung et al.
Chemotherapy, 42(3), 199-205 (1996-05-01)
We demonstrated, for the first time, that the flavonoid purpurogallin (PPG) at 0.2-0.5 mM inhibits DNA synthesis of murine fibrosarcoma L-929 and human U-87 MG glioblastoma cells in vitro. In the human U-87 MG glioblastoma cell experiments, we found that
Kaori Miyazaki et al.
The Tohoku journal of experimental medicine, 203(4), 319-330 (2004-08-07)
The aim of this study was to investigate the oxido-reductive reactions of human hemoglobin with pyrogallol and the metabolism of pyrogallol by the protein, which contains a protoporphyrin IX like cytochrome P-450. Pyrogallol, having three hydroxy groups at the adjacent
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