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Sigma-Aldrich

5(6)-Carboxyfluorescein diacetate

BioReagent, suitable for fluorescence, ≥90.0% (HPLC)

Synonyme(s) :

5(6)-Carboxy-di-O-acetylfluorescein

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About This Item

Formule empirique (notation de Hill):
C25H16O9
Numéro CAS:
124387-19-5
Poids moléculaire :
460.39
Numéro MDL:
MFCD00467494
Code UNSPSC :
12352108
ID de substance PubChem :
329752214
Nomenclature NACRES :
NA.32

Gamme de produits

BioReagent

Niveau de qualité

100

Pureté

≥90.0% (HPLC)

Forme

powder

Solubilité

DMSO: soluble

Fluorescence

λex 492 nm; λem 517 nm in 0.1 M Tris pH 8.0 (esterase)

Adéquation

suitable for fluorescence

Température de stockage

2-8°C

Chaîne SMILES 

CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccc(cc45)C(O)=O)c1.CC(=O)Oc6ccc7c(Oc8cc(OC(C)=O)ccc8C79OC(=O)c%10cccc(C(O)=O)c9%10)c6

InChI

1S/2C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25;1-12(26)31-14-6-8-18-20(10-14)33-21-11-15(32-13(2)27)7-9-19(21)25(18)22-16(23(28)29)4-3-5-17(22)24(30)34-25/h2*3-11H,1-2H3,(H,28,29)

Clé InChI

SWRGCNMDGRMQGB-UHFFFAOYSA-N

Catégories apparentées

Description générale

5(6)-Carboxyfluorescein diacetate or CDFDA is a fluorescent oxidant sensing probe. It is an intracellular probe added to the cells as a pro-substrate, which upon hydrolysis by the esterase enzyme produces the fluorescent product called CDF.

Application

5(6)-Carboxyfluorescein diacetate (CFDA) is a dye which is been extensively utilized to label cultured neurons with the essential requirements, in a specific manner.

5(6)- Carboxyfluorescein diacetate (CFDA) is a viability probe that assesses enzymatic activity, which is necessary to activate its fluorescence, and cell-membrane integrity, which is necessary for the retention of their fluorescent product within the cell.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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The New phytologist, 215(2), 699-710 (2017-04-07)
The interactions of vector-virus-plant have important ecological and evolutionary implications. While the tripartite interactions have received some attention, little is known about whether vector infestation affects subsequent viral transmission and infection. Working with the whitefly Bemisia tabaci, begomovirus and tobacco/tomato
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