700002P

F7-Cholesterol

Avanti Research^™ - A Croda Brand

• Synonyme(s) : 25,26,26,26,27,27,27-heptafluorocholesterol
• Formule empirique (notation de Hill) : C₂₇H₃₉OF₇
• Numéro CAS: 153463-21-9
• Poids moléculaire : 512.59
• Numéro MDL: MFCD28143665
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Essai: >99% (TLC)
• Forme: powder
• Conditionnement: pkg of 1 × 5 mg (700002P-5mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: FC(F)(F)C(F)(C(F)(F)F)CCC[C@H]([C@@H]1[C@@]2([C@H]([C@H]3[C@@H]([C@]4(CC[C@@H](CC4=CC3)O)C)CC2)CC1)C)C
• InChI: 1S/C27H39F7O/c1-16(5-4-12-25(28,26(29,30)31)27(32,33)34)20-8-9-21-19-7-6-17-15-18(35)10-13-23(17,2)22(19)11-14-24(20,21)3/h6,16,18-22,35H,4-5,7-15H2,1-3H3/t16-,18+,19+,20-,21+,22+,23+,24-/m1/s1
• Clé InChI: DUAIJEYNEJQOCE-OLSVQSNTSA-N

Description

Description générale

F7-Cholesterol is a fluorinated derivative of cholesterol.[1] It is a cholesterol analog.[2] F7-Cholesterol is useful as helper lipid in conjunction with vectors for DNA transfection.[3]

Application

F7-Cholesterol has been used:

• in the preparation of liposomes for DNA delivery studies[4]
• to investigate its rescue functionality in hedgehog signaling in sterol-depleted cells[1]
• in preparation of monolayers for pressure and area isotherms studies[3]

Actions biochimiques/physiologiques

F7-Cholesterol has potential biological applications.[2] It has a negative dipole moment.[5] F7-Cholesterol rescues hedgehog signaling in sterol-depleted cells.[1] The molecular orientation and phospholipid interaction of F7-cholesterol is similar to hydrogenated cholesterol.[6]

Conditionnement

5 mL Amber Glass Screw Cap Vial (700002P-5mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids