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1046001

USP

Azathioprine

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine

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About This Item

Fórmula empírica (Notação de Hill):
C9H7N7O2S
Número CAS:
446-86-6
Peso molecular:
277.26
Número MDL:
MFCD00069203
Código UNSPSC:
41116107
ID de substância PubChem:
329749088
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

azathioprine

fabricante/nome comercial

USP

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Cn1cnc(c1Sc2ncnc3[nH]cnc23)[N+]([O-])=O

InChI

1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)

chave InChI

LMEKQMALGUDUQG-UHFFFAOYSA-N

Informações sobre genes

human ... PPAT(5471)

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Azathioprine USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Azathioprine Tablets
  • Azathioprine Sodium for Injection
  • Azathioprine Compounded Oral Suspension

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

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Pictogramas

Health hazardExclamation mark
GHS08,GHS07

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

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Mattheus C B Wielenga et al.
World journal of gastroenterology, 20(44), 16683-16689 (2014-12-04)
To investigate if azathioprine could reduce adenoma formation in Apc(Min/+) , a mouse model of sporadic intestinal tumorigenesis. Azathioprine was administered via drinking water (estimated 6-20 mg/kg body weight per day) to Apc(Min/+) and wildtype mice. Control animals received vehicle
Divya Balakrishnan et al.
Seminars in ophthalmology, 30(2), 157-159 (2013-10-15)
The purpose of this study is to report a case of atypical serpiginous choroiditis presenting with disc edema and exudative retinal detachment, treated successfully with intravenous methyl prednisolone. A 45-year-old male patient presented with sudden decrease of vision in his
Rong Fan et al.
World journal of gastroenterology, 20(39), 14479-14487 (2014-10-24)
To assess "top-down" treatment for deep remission of early moderate to severe Crohn's disease (CD) by double balloon enteroscopy. Patients with early active moderate to severe ileocolonic CD received either infusion of infliximab 5 mg/kg at weeks 0, 2, 6
Ehren N Rudolph et al.
Transplantation, 99(2), 367-374 (2015-01-17)
Pancreas retransplantation is associated with increased rates of technical failure and rejection compared to other organ transplants. As such, it is not routinely done, and outcomes are mostly known through registry data. Here we analyze the outcomes of primary versus
Didier Ducloux et al.
Transplantation, 99(1), 220-225 (2014-10-07)
Chronic exposure to exogenous antigens causes accumulation of proinflammatory CD57(+)CD28(-) hyperactivated CD8(+) T cells that may promote atherosclerosis. We hypothesized that persistent alloimmune responses may induce immune activation and contribute to posttransplant atherosclerosis. This hypothesis was tested in a single-center
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