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47889

Supelco

Metil 4-hidroxibenzoato

PESTANAL®, analytical standard

Sinônimo(s):

Éster metílico de ácido p-hidroxibenzoico, Metilparabeno, NIPAGIN

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About This Item

Fórmula linear:
HOC6H4CO2CH3
Número CAS:
99-76-3
Peso molecular:
152.15
Beilstein:
509801
Número CE:
202-785-7
Número MDL:
MFCD00002352
Código UNSPSC:
12164500
ID de substância PubChem:
24871585
Número E:
E218
Preço e disponibilidade não estão disponíveis no momento.

grau

analytical standard

linha de produto

PESTANAL®

Certificado de análise (CofA)

current certificate can be downloaded

embalagem

ampule of 1000 mg

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

125-128 °C (lit.)

aplicação(ões)

cleaning products
cosmetics
food and beverages
personal care

Formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

chave InChI

LXCFILQKKLGQFO-UHFFFAOYSA-N

Informações sobre genes

rat ... Ar(24208)

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Categorias relacionadas

Descrição geral

Methyl Paraben is a stable, non-volatile[1], methyl ester of p-hydroxybenzoic acid[1][2]. It can find applications as a broad-spectrum antimicrobial preservative in foods, drugs and cosmetics.[1][2] It is found to be noncarcinogenic and is highly effective against fungi like molds and yeast as well as bacteria.[1][2]
Methyl paraben is basically a methyl ester of p-hydroxybenzoic acid. It is non-toxic, and non-carcinogenic in nature. It is a stable, non-volatile compound and finds application as an anti-microbial preservative in foods, drugs and cosmetics. It is readily absorbed through the skin and gastrointestinal tract. Upon hydrolyzation, it is hydrolyzed to p-hydroxybenzoic acid, and the conjugates formed get rapidly excreted in the urine.[3]

Aplicação

Methyl paraben was used a preservative standard in commercial food products, during an experimental investigation, done to study the application of microemulsion electrokinetic chromatography (MEEKC), in detecting food preservatives.[4]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações legais

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogramas

Environment
GHS09

Frases de perigo

H411

Declarações de precaução

P273 - P391 - P501

Classificações de perigo

Aquatic Chronic 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

334.4 °F

Ponto de fulgor (°C)

168 °C

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
LC26909V
LC25781V
LC24623V
LC23150V
LC21963V

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Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

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Sigma-Aldrich

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Sigma-Aldrich

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SAFC

1.06757

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Supelco

05828

Isopropyl 4-hydroxybenzoate

Evaluation of the health aspects of methyl paraben: a review of the published literature
Soni.G.M, et al.
Food And Chemical Toxicology, 40, 1335-1373 (2002)
Chul-Hong Kim et al.
Genes, 12(2) (2021-03-07)
Bisphenol A (BPA) is a xenoestrogen chemical commonly used to manufacture polycarbonate plastics and epoxy resin and might affect various human organs. However, the cellular effects of BPA on the eyes have not been widely investigated. This study aimed to
Evaluation of the health aspects of methyl paraben: a review of the published literature.
Soni MG
Food And Chemical Toxicology, 40 (10), 1335-1373 (2002)
Application of microemulsion electrokinetic chromatography for the detection of preservatives in foods.
Huang H.y
Food Chemistry, 89 (2), 315-322 (2005)
Combined activation of methyl paraben by light irradiation and esterase metabolism toward oxidative DNA damage
Okamoto Y, et al.
Chemical Research in Toxicology, 21, 1594-1599 (2008)
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Questions

1–5 of 5 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  4. How is Product No. 47889 EPA 8040A Phenol Calibration Mix packaged?

    1 answer

    1. Product No. 47889 comes packaged in a 4ml amber vial with teflon lined solid cap.

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  5. What is Product No. 47889 EPA 8040A Phenol Calibration Mix soluble in?

    1 answer

    1. Product No. 47889 EPA 8040A Phenol Calibration Mix is slightly soluble in water and soluble in alcohol, diethyl ether, and acetone

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