SRP6081
TXNRD1 human
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Sinônimo(s):
GRIM-12, MGC9145, TR1, TRXR1, Thioredoxin reductase
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About This Item
Produtos recomendados
fonte biológica
human
recombinante
expressed in E. coli
Ensaio
≥95% (SDS-PAGE)
forma
liquid
potência
0.48 units/mL
peso molecular
55.7 kDa
embalagem
pkg of 100 μg
nº de adesão NCBI
Condições de expedição
dry ice
temperatura de armazenamento
−70°C
Informações sobre genes
human ... TXNRD1(7296)
Descrição geral
Thioredoxin reductase 1 (TNXRD1), cytoplasmic is an enzyme in humans that is encoded by the TXNRD1 gene. This gene encodes a member of the family of pyridine nucleotide oxidoreductases and is localized on human chromosome 12.
Ações bioquímicas/fisiológicas
Thioredoxin reductase 1 (TNXRD1) reduces thioredoxins as well as other substrates. It plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses flavin adenine dinucleotide (FAD) as a cofactor. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, acquired immune deficiency syndrome (AIDS), autoimmune diseases as well as bacterial infections and parasitic diseases.
forma física
0.5 mg/mL solution in PBS (pH 7.4) containing 20% glycerol.
Nota de preparo
Centrifuge the vial prior to opening.
Outras notas
MGSSHHHHHH SSGLVPRGSH MYDYDLIIIG GGSGGLAAAK EAAQYGKKVM VLDFVTPTPL GTRWGLGGTC VNVGCIPKKL MHQAALLGQA LQDSRNYGWK VEETVKHDWD RMIEAVQNHI GSLNWGYRVA LREKKVVYEN AYGQFIGPHR IKATNNKGKE KIYSAERFLI ATGERPRYLG IPGDKEYCIS SDDLFSLPYC PGKTLVVGAS YVALECAGFL AGIGLDVTVM VRSILLRGFD QDMANKIGEH MEEHGIKFIR QFVPIKVEQI EAGTPGRLRV VAQSTNSEEI IEGEYNTVML AIGRDACTRK IGLETVGVKI NEKTGKIPVT DEEQTNVPYI YAIGDILEDK VELTPVAIQA GRLLAQRLYA GSTVKCDYEN VPTTVFTPLE YGACGLSEEK AVEKFGEENI EVYHSYFWPL EWTIPSRDNN KCYAKIICNT KDNERVVGFH VLGPNAGEVT QGFAAALKCG LTKKQLDSTI GIHPVCAEVF TTLSVTKRSG ASILQAGC
Código de classe de armazenamento
13 - Non Combustible Solids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
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