Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

SML1555

Sigma-Aldrich

MS023 hydrochloride

≥98% (HPLC)

Sinônimo(s):

N1-((4-(4-Isopropoxyphenyl)-1H-pyrrol-3-yl)methyl)-N1-methylethane-1,2-diamine hydrochloride, N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine hydrochloride

Faça loginpara ver os preços organizacionais e de contrato

Selecione um tamanho

5 MG
R$ 1.389,00
25 MG
R$ 5.576,00

R$ 1.389,00


Check Cart for Availability

Solicite uma grande encomenda

Selecione um tamanho

Alterar visualização
5 MG
R$ 1.389,00
25 MG
R$ 5.576,00

About This Item

Fórmula empírica (Notação de Hill):
C17H25N3O · xHCl
Número CAS:
Peso molecular:
287.40 (free base basis)
Código UNSPSC:
12352200
ID de substância PubChem:
NACRES:
NA.77

R$ 1.389,00


Check Cart for Availability

Solicite uma grande encomenda

Nível de qualidade

Ensaio

≥98% (HPLC)

Formulário

powder

condição de armazenamento

desiccated

cor

white to light brown

solubilidade

H2O: 20 mg/mL, clear

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CN(CCN)CC1=CNC=C1C2=CC=C(OC(C)C)C=C2.[H]Cl

InChI

1S/C17H25N3O.ClH/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18;/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3;1H

chave InChI

IEZPALXFXHDDHI-UHFFFAOYSA-N

Categorias relacionadas

Ações bioquímicas/fisiológicas

MS023 is a potent and selective chemical probe for Type I protein arginine methyltransferases (PRMTs).
MS023 is a potent and selective chemical probe for Type I protein arginine methyltransferases (PRMTs). MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues. MS023 is active in cells. For full characterization details, please visit the MS023 probe summary on the Structural Genomics Consortium (SGC) website.

To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc

Características e benefícios

MS023 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Outras notas

MS023 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the MS023 probe summary on the Chemical Probes Portal website.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 1

1 of 1

(+)-JQ1 ≥98% (HPLC)

Sigma-Aldrich

SML1524

(+)-JQ1

Fangrong Zhang et al.
Cell reports methods, 1(2), 100016-100016 (2022-04-28)
Quantitative information about the levels and dynamics of post-translational modifications (PTMs) is critical for an understanding of cellular functions. Protein arginine methylation (ArgMet) is an important subclass of PTMs and is involved in a plethora of (patho)physiological processes. However, because
Pan-methylarginine antibody generation using PEG linked GAR motifs as antigens.
Wang, et al.
Methods, 200, 80-86 (2023)
Edward M Courchaine et al.
Cell, 184(14), 3612-3625 (2021-06-12)
Biomolecular condensation is a widespread mechanism of cellular compartmentalization. Because the "survival of motor neuron protein" (SMN) is implicated in the formation of three different membraneless organelles (MLOs), we hypothesized that SMN promotes condensation. Unexpectedly, we found that SMN's globular
Carolina N Franco et al.
Science advances, 9(36), eadi2232-eadi2232 (2023-09-08)
Vitamin B6 is a vital micronutrient across cell types and tissues, and dysregulated B6 levels contribute to human disease. Despite its importance, how B6 vitamer levels are regulated is not well understood. Here, we provide evidence that B6 dynamics are

Artigos

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

Questions

Reviews

No rating value

Active Filters

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica