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RAB1284

Sigma-Aldrich

Human BAMBI ELISA

for serum, plasma and cell culture supernatants

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1 KIT
R$ 5.181,00

R$ 5.181,00


Previsão de entrega em09 de abril de 2025



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R$ 5.181,00

About This Item

Código UNSPSC:
41116158
NACRES:
NA.32

R$ 5.181,00


Previsão de entrega em09 de abril de 2025


reatividade de espécies

human

técnica(s)

ELISA: suitable

entrada

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

Informações sobre genes

human ... BAMBI(25805)

Descrição geral

BAMBI (bone morphogenic protein and activin membrane-bound inhibitor) gene codes for a transmembrane glycoprotein which is a pseudo receptor belonging to the family of TGF-β (transforming growth factor β receptor) type I receptors.[1][2] BAMBI is predominantly expressed in placenta, spleen and kidney medulla and also found liver, prostate, gut and kidney cortex.[1]
This ELISA antibody pair detects Human BAMBI. Other species not yet determined.

Aplicação

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Ações bioquímicas/fisiológicas

BAMBI (bone morphogenic protein and activin membrane-bound inhibitor) acts as an inhibitor of TGF-β (transforming growth factor β receptor) signalling which causes epithelial-mesenchymal transition.[1] Upregulation of BAMBI gene is observed in chronic obstructive pulmonary disease and a number of cancer including thyroid, liver, colorectal cancer and ovarian cancer.[3][4] BAMBI might regulate the events of inflammation and remodeling processes.[3]

Outras notas

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pictogramas

Corrosion

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Met. Corr. 1

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia
Yao H, et al.
Scientific Reports, 6, 27051-27051 (2016)
Dysregulation of the Transforming Growth Factor β Pathway in Induced Pluripotent Stem Cells Generated from Patients with Diamond Blackfan Anemia
Jingping G, et al.
PLoS ONE, 10(8), e0134878-e0134878 (2015)
Downregulation of the TGFβ Pseudoreceptor BAMBI in Non?Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion.
Marwitz S, et al.
Cancer Research (2016)
Kai Liu et al.
Molecular medicine reports, 10(2), 874-880 (2014-06-11)
The upregulation of bone morphogenetic protein and activin membrane‑bound inhibitor (BAMBI) has been observed in several types of malignant cancer, including thyroid, ovarian, liver and colorectal cancer. However, the pathological role and the regulatory mechanism of BAMBI in gastric cancer

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