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RAB0460

Sigma-Aldrich

Human TGF-β 1 ELISA Kit

Human TGF-β 1 ELISA Kit

for serum, plasma, and cell culture supernatants

Sinônimo(s):

TGF-beta-1, Transforming growth factor beta-1

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About This Item

Código UNSPSC:
41116158
NACRES:
NA.32
Preço e disponibilidade não estão disponíveis no momento.

reatividade de espécies

human

embalagem

kit of 96 wells (12 strips x 8 wells)

técnica(s)

ELISA: suitable
capture ELISA: suitable

entrada

sample type serum
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 0.0823-60 ng/mL

método de detecção

colorimetric

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

Informações sobre genes

human ... TGFB1(7040)

Categorias relacionadas

Descrição geral

The Human TGF-β 1 ELISA (Enzyme-Linked mmunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human TGF-β 1 in serum, plasma, cell culture supernatants.

Imunogênio

Recombinant Human TGF-β 1

Aplicação

For research use only. Not for use in diagnostic procedures.
Human transforming growth factor-β1 (TGF-β1) ELISA Kit has been used to measure level of TGF-β1 released from tubular cells.[1]

Ações bioquímicas/fisiológicas

Transforming growth factor-β1 (TGF-β1) is a pluripotential cytokine that plays a vital role in the homeostasis of peripheral CD4+CD25+ regulatory T cells and regulation of FOXP3 (forkhead box P3) expression in vivo. Binding of TGF-β1 to its receptor, activates members of the SMAD protein family involved in gene regulation.[2] Study shows that reduced expression of circulating transforming growth factor-β1 (TGF-β1) might contribute to systemic lupus erythematosus (SLE) development. Polymorphism of TGF-β1 is associated with pathogenesis of rheumatoid arthritis (RA) and pneumoconiosis.[3][4] Serum TGF-β1 expression is elevated in systemic sclerosis (SSc) patients.[5] Serum TGF-β1 functions as a potential biomarker of Guillain-Barré syndrome (GBS) and SSc.[5][6]

Outras notas

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Componentes do kit também disponíveis separadamente

Nº do produto
Descrição
SDS

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pictogramas

Corrosion

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Met. Corr. 1

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials


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Certificados de análise (COA)

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Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

XueXuan Zhang et al.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 59, 110-117 (2017-04-19)
To investigate PI3K-Akt-mTOR signaling pathway changes and the proliferation of FoxP3+Treg cells in patients with active tuberculosis. We isolated PBMCs and CD4+CD25+FoxP3+Treg cells from peripheral blood collected from patients with active tuberculosis and healthy controls. We compared the proportion and
Qiao Huang et al.
Experimental and therapeutic medicine, 18(1), 692-698 (2019-07-02)
NEF is a tumor suppressing long non-coding (lnc)RNA in hepatocellular carcinoma. Based on current literature, the involvement of NEF in other human diseases is still unknown. The current study aimed to investigate the potential involvement of NEF in glioma, which
Association between Genetic Variants of Transforming Growth Factor-?1 and Susceptibility of Pneumoconiosis: A Meta-analysis.
Deng CW
Chinese Medical Journal (English Edition), 130(3), 357-364 (2017)
Reassessing the Role of the Active TGF-?1 as a Biomarker in Systemic Sclerosis: Association of Serum Levels with Clinical Manifestations.
Dantas AT
Disease Markers (2016)
Association between circulating transforming growth factor-?1 level and polymorphisms in systemic lupus erythematosus and rheumatoid arthritis: A meta-analysis.
Lee YH and Bae SC
Cellular and molecular biology (Noisy-le-Grand, France), 63(1), 53-59 (2017)

Questions

Reviews

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    • Review 1
    • Votes 0
    1 out of 5 stars.

    Do not recommend

    Does not come with the user guide. Tried to find it online and could not find it. It is so tedious.

    Helpful?

    1. Response from MilliporeSigma:

      The protocol for RAB0460 is listed on the COA and is consistent from lot to lot. We apologize the document was not easily accessible on our website and are making adjustments for easy access to a sample COA. In the meantime, please reach out to technical service for a copy.

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