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R4632

Sigma-Aldrich

Retinyl acetate

synthetic, crystalline solid or supercooled liquid

Sinônimo(s):

Retinol acetate, Vitamin A acetate

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1 G
R$ 614,00
5 G
R$ 1.043,00
25 G
R$ 3.037,00
100 G
R$ 8.252,00

R$ 614,00


Disponível para enviar em10 de abril de 2025Detalhes


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Selecione um tamanho

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1 G
R$ 614,00
5 G
R$ 1.043,00
25 G
R$ 3.037,00
100 G
R$ 8.252,00

About This Item

Fórmula empírica (Notação de Hill):
C22H32O2
Número CAS:
Peso molecular:
328.49
Beilstein:
1915439
Número CE:
Número MDL:
Código UNSPSC:
12352205
eCl@ss:
34058009
ID de substância PubChem:
NACRES:
NA.79

R$ 614,00


Disponível para enviar em10 de abril de 2025Detalhes


Solicite uma grande encomenda

fonte biológica

synthetic

Ensaio

≥90% (HPLC)

Formulário

crystalline solid or supercooled liquid

potência

2,600,000-2,940,000 I.U. per g

cor

light yellow to dark yellow

pf

57-58 °C
~58 °C (lit.)

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

chave InChI

QGNJRVVDBSJHIZ-QHLGVNSISA-N

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Descrição geral

Vitamin A usually occurs in food as retinyl esters,[1] which are the pre-formed sources of vitamin A.[2] Retinyl acetate exists as yellow crystals and is insoluble in water. It is soluble in ethanol and oils.[3]

Aplicação

Retinyl acetate has been used:
  • to study its effects on cochlear development in mice[4]
  • as a component of an internal standard to quantify antioxidants in yolk[4]
  • as an internal standard to determine serum retinol concentration[5]

Ações bioquímicas/fisiológicas

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed. Retinyl acetate is used in a wide range of biological applications.

forma física

Packaged as a melt and may exist as a crystalline solid or a supercooled viscous liquid

Nota de análise

Activity based on HPLC comparison to USP standard.

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Aquatic Chronic 4 - Repr. 1B

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Certificados de análise (COA)

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Effects of retinoid treatment on cochlear development, connexin expression and hearing thresholds in mice
Kim Yy, et al.
Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'Oto-rhino-laryngologie et de Chirurgie Cervico-Faciale (2018)
Capillary electrophoresis Food Additives
Frazier RA
Encyclopedia of Separation Science (2007)
Assessment of the relative dose-response test based on serum retinol-binding protein instead of serum retinol in determining low hepatic vitamin A stores
Fujita M, et al.
American Journal of Clinical Nutrition (2009)
Buhler Volker
Vademecum for Vitamin Formulations (2001)

Artigos

All-trans retinoic acid (RA, ATRA) is a pleiotropic activation factor that regulates genes associated with normal vertebrate cellular processes such as cell differentiation, cell proliferation, apoptosis, and embryonic development.

Protocolos

GB method with Ascentis® Express C30 column achieves baseline resolution for Vitamin A and E critical pair.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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