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R3250

Sigma-Aldrich

Retinyl acetate

synthetic, matrix dispersion, 475,000-650,000 USP units/g

Sinônimo(s):

Retinol acetate, Vitamin A acetate

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About This Item

Fórmula empírica (Notação de Hill):
C22H32O2
Número CAS:
127-47-9
Peso molecular:
328.49
Beilstein:
1915439
Número CE:
204-844-2
Número MDL:
MFCD00019413
Código UNSPSC:
12352205
eCl@ss:
34058009
ID de substância PubChem:
57654589
NACRES:
NA.79

fonte biológica

synthetic

forma

matrix dispersion

atividade específica

475,000-650,000 USP units/g

cor

yellow

pf

57-58 °C

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

chave InChI

QGNJRVVDBSJHIZ-QHLGVNSISA-N

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Descrição geral

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate.

Aplicação

Retinyl acetate has been used:
  • a control diet to study its effect at different developmental periods in fish larvae
  • to study its inhibitory effects on Mycobacterium avium subspecies paratuberculosis (MAP) strains
  • as an internal standard in high performance liquid chromatography (HPLC) to quantify vitamin A in fortified milk

Ações bioquímicas/fisiológicas

Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as required. Retinyl acetate is used in a wide range of biological applications. It acts as a chemopreventive agent. Retinyl acetate also has antineoplastic property.

forma física

Dispersion in cornstarch-gelatin matrix. Oil dispersible

Nota de análise

Activity based on HPLC comparison to USP standard.

Pictogramas

Health hazard
GHS08

Palavra indicadora

Danger

Frases de perigo

H360D,H413

Classificações de perigo

Aquatic Chronic 4 - Repr. 1B

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Retinol ≥95.0% (HPLC), ~2700 U/mg

Sigma-Aldrich

17772

Retinol

Retinyl palmitate potency: ≥1,700,000 USP units per g

Sigma-Aldrich

R1512

Retinyl palmitate

5-α-colestano certified reference material, 10 mg/mL in chloroform

Supelco

47124

5-α-colestano

(−)-Riboflavina meets USP testing specifications

Sigma-Aldrich

R7649

(−)-Riboflavina

Supelco

Supelco

46959-U

Retinol palmitate

Retinol BioXtra, ≥97.5% (HPLC), ~3100 U/mg

Sigma-Aldrich

95144

Retinol

Vitamins A & D inhibit the growth of mycobacteria in radiometric culture
Greenstein RJ, et al.
PLoS ONE, 7(1), e29631-e29631 (2012)
A survey of vitamin A and D contents of fortified fluid milk in Ontario
Faulkner H, et al.
Journal of Dairy Science, 83(6), 1210-1216 (2000)
Effect of combined selenium and retinyl acetate treatment on mammary carcinogenesis
Thompson HJ, et al.
Cancer Research, 41(4), 1413-1416 (1981)
Intake of high levels of vitamin A and polyunsaturated fatty acids during different developmental periods modifies the expression of morphogenesis genes in European sea bass (Dicentrarchus labrax)
Villeneuve LAN, et al.
The British Journal of Nutrition, 95(4), 677-687 (2006)
Laure A N Villeneuve et al.
The British journal of nutrition, 95(4), 677-687 (2006-03-31)
The effect of the feeding period on larval development was investigated in European sea bass larvae by considering the expression level of some genes involved in morphogenesis. Larvae were fed a control diet except during three different periods (period A:
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