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P2918

Sigma-Aldrich

Soro humano

from platelet poor human plasma, sterile-filtered, (mycoplasma tested, virus tested)

Sinônimo(s):

human plasma, human sera, human serum

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About This Item

Número MDL:
Código UNSPSC:
12352207
NACRES:
NA.71

fonte biológica

human

esterilidade

sterile-filtered

origem

USA origin

técnica(s)

cell culture | mammalian: suitable

Impurezas

(mycoplasma tested, virus tested)
≤10 EU/mL endotoxin

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

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Descrição geral

The serum is the fluid part of the blood containing plasma without fibrinogen.

Aplicação

Human Serum has been used:
  • in the preparation of human serum samples that mimic the COVID-19 patient samples for serological antibody testing
  • as a media supplement to differentiate human induced pluripotent stem cells (hiPS) to hiPS- brain microvascular endothelial cells (BMEC)
  • for culturing transgenic Plasmodium falciparum clone
  • for assessing the electrochemical response of recombinant P. falciparum parasite L-lactate dehydrogenase (LDH) in serum samples
  • in platelet-derived growth factor (PDGF) purification assays

Human serum from platelet poor plasma (PPP) is useful for studies of the effects of platelet lysates on the growth of cells such as articular chondrocytes and human skin fibroblasts. It has also been used in platelet derived growth factor (PDGF) purification assays.

Ações bioquímicas/fisiológicas

Serum serves as a supplement to basal media formulations and conventional biomedical cell culture media. It acts as a source of trace nutrients, signaling molecules, growth factors, and hormones that induce proper cell growth in vitro. Human serum from platelet-poor plasma (PPP) is useful in the studies of the effects of platelet lysates on the growth of cells such as articular chondrocytes and human skin fibroblasts.

Nota de análise

Testado quanto à presença de endotoxinas

Outras notas

It is not unusual for a white precipitate to form following a freeze-thaw cycle for this human serum product.

Exoneração de responsabilidade

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Physiology, Blood Plasma null
Aver Hemben et al.
Talanta, 187, 321-329 (2018-06-02)
This paper describes the development of an affinity sensor for the detection of Plasmodium falciparum parasite lactate dehydrogenase (pLDH) as one of the biomarkers used for malaria detection. The gold sensor was functionalised with anti-pLDH after cleaning the electrode surface
Y Umeno et al.
Journal of cell science, 94 ( Pt 3), 567-575 (1989-11-01)
We examined the proliferative behaviour in tertiary culture cells of human skin fibroblasts (HSF) as well as cells of the rat 3Y1 diploid fibroblast line placed on a plastic substratum in a nutrient-rich medium containing high concentrations of platelet-poor plasma
Y C Choi et al.
Arthritis and rheumatism, 23(2), 220-224 (1980-02-01)
Human platelet lysate (PL) has a strong growth promoting action on rabbit articular chondrocytes in monolayer culture. The responsible factor is heat stable (56 degrees C, 30 minutes) and above 10,000 MW. PL (80 microgram protein/ml) reduces cell protein content
Edward N O'Neill et al.
Comprehensive reviews in food science and food safety, 20(1), 686-709 (2020-12-17)
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Artigos

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