I9401
Interleukin-1β human
IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Sinônimo(s):
IL-1β, Lymphocyte activating factor
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About This Item
Número MDL:
Código UNSPSC:
12352202
Produtos recomendados
fonte biológica
human
Nível de qualidade
recombinante
expressed in E. coli
Ensaio
≥98% (SDS-PAGE)
Formulário
lyophilized powder
potência
≤12 pg/mL ED50
qualidade
endotoxin tested
peso molecular
17.3 kDa
embalagem
pkg of 5 and 25 μg
pkg of 25 μg
técnica(s)
cell culture | mammalian: suitable
cor
white to off-white
nº de adesão UniProt
temperatura de armazenamento
−20°C
Informações sobre genes
human ... IL1B(3553)
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Ações bioquímicas/fisiológicas
Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LAF), activates T cell lymphocytes, which then proliferate and secrete interleukin-2 (IL-2). IL-1 is released primarily from stimulated macrophages and monocytes, but has also been shown to be released from several other types and is thought to play a key role in inflammatory and immune responses. Other synonyms for IL-1 include: endogenous pyrogen (EP), mitogenic protein (MP), Helper Peak-1 (HP-1), T Cell Replacing Factor III (TRF III or TRFM), B Cell Activating Factor (BAF) and B Cell Differentiation Factor (BDF) The two closely related agents Interleukin-1α (IL-1α) and Interleukin-1β (IL-1β) share 62% homology in amino acid sequence and elicit nearly identical biological responses. IL-1α and IL-1β are both approximately 17 kDa with some heterogeneity in the amount of glycosylation.
forma física
Lyophilized from a 0.2 μm filtered buffered solution.
Nota de análise
The biological activity is measured by the dose-dependent stimulation of MTS cleavage by murine D10S cells.
Código de classe de armazenamento
13 - Non Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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