G9910

Sodium glycodeoxycholate

BioXtra, ≥97% (HPLC)

• Sinônimo(s): 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide, Glycodeoxycholic acid sodium salt, Glycodesoxycholic acid, N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine
• Fórmula empírica (Notação de Hill): C₂₆H₄₂NNaO₅
• Número CAS: 16409-34-0
• Peso molecular: 471.61
• Número CE: 240-455-4
• Número MDL: MFCD00036742
• Código UNSPSC: 12161900
• ID de substância PubChem: 24895386
• NACRES: NA.25

Propriedades

• descrição: anionic
• Nível de qualidade: 200
• linha de produto: BioXtra
• Ensaio: ≥97% (HPLC)
• peso molecular: 471.61 g/mol
• Impurezas: ≤0.0025% Phosphorus (P); ≤0.1% Insoluble matter
• CMC: 2.1 mM
• solubilidade: H₂O: 0.1 M, clear to slightly hazy, colorless to almost colorless
• traços de ânion: chloride (Cl^-): ≤1%; sulfate (SO₄^2-): ≤0.05%
• traços de cátion: Al: ≤0.0005%; Ca: ≤0.011%; Cu: ≤0.0005%; Fe: ≤0.001%; K: ≤0.005%; NH₄⁺: ≤0.05%; Pb: ≤0.001%; Zn: ≤0.003%
• cadeia de caracteres SMILES: [Na].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@]([H])([C@H](C)CCC(=O)NCC(O)=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C26H43NO5.Na.H/c1-15(4-9-23(30)27-14-24(31)32)19-7-8-20-18-6-5-16-12-17(28)10-11-25(16,2)21(18)13-22(29)26(19,20)3;;/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);;/t15-,16-,17-,18+,19-,20+,21+,22+,25+,26-;;/m1../s1
• chave InChI: BMYWWGPEKRLDGW-ZXMGEDLUSA-N

Descrição

Descrição geral

Sodium glycodeoxycholate is a bile salt that can be used to form biomimicking environments. [1]

Aplicação

Sodium glycodeoxycholate has been used in a study to develop more similar mimetic intestinal fluids to physiological fluids than those developed by mixed bile salt systems (MBS). [2] It has also been used in a study to investigate Ca²⁺ buffering capability of bile salt micelles. [3]

Ações bioquímicas/fisiológicas

Induces apoptosis in hepatocytes; may induce DNA cleavage.

Outras notas

Bile Salt

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves