580549

Tauroursodeoxycholic Acid, Sodium Salt

Tauroursodeoxycholic is a detergent useful for the solubilization of lipids and membrane-bound proteins.

• Sinônimo(s): Tauroursodeoxycholic Acid, Sodium Salt, Sodium Tauroursodeoxycholate
• Fórmula empírica (Notação de Hill): C₂₆H₄₄NO₆S · Na
• Número CAS: 35807-85-3
• Peso molecular: 521.69
• Código UNSPSC: 12352106
• NACRES: NA.21

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥97% (TLC)
• forma: solid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze
• cor: white
• solubilidade: water: 100 mg/mL
• Condições de expedição: ambient
• temperatura de armazenamento: 15-25°C
• InChI: 1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20?,21?,22+,24?,25+,26-/m1/s1
• chave InChI: BHTRKEVKTKCXOH-AYSJQVDDSA-N

Descrição

Descrição geral

Detergent useful for the solubilization of lipids and membrane–bound proteins.

Detergent useful for the solubilization of lipids and membrane-bound proteins. Has cryoprotective effects against hydrophobic bile salts in rats. Also reported to inhibit pepsin activity in vitro.

Aplicação

• Inhibition of endoplasmic reticulum stress combined with activation of angiotensin-converting enzyme 2: novel approach for the prevention of endothelial dysfunction in type 1 diabetic rats.: This study highlights the efficacy of tauroursodeoxycholic acid, sodium salt in reducing endoplasmic reticulum stress, suggesting its utility in preventing vascular complications in diabetes (Gaikwad AB et al., 2022).

Advertência

Toxicity: Standard Handling (A)

Outras notas

Ozcan, U., et al. 2006. Science313, 1137.
Miyake, H., et al. 1999. Dig. Dis. Sci.44, 197.
Eto, T. and Tompkins, R.K. 1985. Am. J. Surg.150, 564.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable